Evidence-based renewal of the Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons

The Italian Society for Infectious and Tropical Diseases (SIMIT) in collaboration with the Technical Health Committee (Sections L and M) of the Italian Ministry of Health have supported the renewal of the recommendations for the Italian guidelines for the use of antiretroviral agents and the diagnos...

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Bibliographic Details
Published in:The New microbiologica 2018-10, Vol.41 (4), p.247-255
Main Authors: Antinori, Andrea, Di Biagio, Antonio, Marcotullio, Simone, Sarmati, Loredana, Andreoni, Massimo, Angarano, Gioacchino, Chirianni, Antonio, d'Arminio Monforte, Antonella, Di Perri, Giovanni, Galli, Massimo, Gianotti, Nicola, Girardi, Enrico, Gori, Andrea, Mussini, Cristina, Perno, Carlo-Federico, Lazzarin, Adriano
Format: Article
Language:English
Subjects:
Anti-HIV Agents - therapeutic use
Antiretroviral agents
Antiviral agents
Diagnostic software
Diagnostic systems
Evaluation
Evidence-Based Medicine
Guidelines
Guidelines as Topic
HIV
HIV Infections - diagnosis
HIV Infections - drug therapy
HIV Seropositivity
HIV-1
Human immunodeficiency virus
Humans
Immunology
Italy
Management
Optimization
Quality
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Summary:The Italian Society for Infectious and Tropical Diseases (SIMIT) in collaboration with the Technical Health Committee (Sections L and M) of the Italian Ministry of Health have supported the renewal of the recommendations for the Italian guidelines for the use of antiretroviral agents and the diagnostic-clinical management of HIV-1 infected persons. This publication summarizes the latest updates to the 2017 version of the Italian Guidelines for the management of HIV-1 infected patients and the use of antiretroviral drugs. New recommendations were released framing the clinical questions the use of antiretrovirals according to the Patient Intervention Comparator Outcome (PICO) methodology and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Diagnostic tools for immunological and virological monitoring, when to start, what to start, optimization and therapeutic failure were updated in order to include the recommendation obtained with these newly developed methods. For a complete review of clinical and therapeutic relevant topics we refer the reader to the extended version of the Guidelines.
ISSN:1121-7138