Paraneoplastic limbic encephalitis revealing a small cell carcinoma of the lung

INTRODUCTIONParaneoplastic limbic encephalitis is a rare disease, usually associated with small cell lung cancer. CASE REPORTWe report in this publication the cases with different age brackets, who presented with various neurological symptoms such as repetitive seizures or anterograde amnesia. Cereb...

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Bibliographic Details
Published in:Respiratory medicine case reports 2019, Vol.26, p.157-160
Main Authors: Kacem, Marwa, Belloumi, Nidhal, Bachouche, Imene, Mersni, Mariem, Chermiti Ben Abdallah, Fatma, Fenniche, Soraya
Format: Report
Language:English
Online Access:Get full text
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Summary:INTRODUCTIONParaneoplastic limbic encephalitis is a rare disease, usually associated with small cell lung cancer. CASE REPORTWe report in this publication the cases with different age brackets, who presented with various neurological symptoms such as repetitive seizures or anterograde amnesia. Cerebral CT-scan, cerebral MRI and anti onco-neural paraneoplastic antibodies were suggesting the diagnosis of paraneoplastic limbic encephalitis. Etiological exploration lead to the diagnosis of locally advanced small cell carcinoma of the lung. We started rapidly a curative protocol associating chemotherapy and sequential thoracic radiotherapy. CONCLUSIONSwe insist on the diversity of the imaging findings, immunological analyses and outcome on treatment of this entity. Prognostic impact remains also unclear.
ISSN:2213-0071
2213-0071
DOI:10.1016/j.rmcr.2018.12.015