Dietary Soy Isoflavone: A Mechanistic Insight

Soy, a major component of the diet for centuries contains the largest concentration of isoflavones, a class of phytoestrogens. A variety of health benefits are associated with the consumption of soy primarily because of the isoflavones genistein, daidzein, and glycitein with a potential protective e...

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Bibliographic Details
Published in:Natural Product Communications 2017-04, Vol.12 (4), p.627-634
Main Authors: Chadha, Renu, Bhalla, Yashika, Jain, Ankita, Chadha, Kunal, Karan, Maninder
Format: Article
Language:English
Subjects:
Animals
Dietary Supplements - analysis
Glycine max - chemistry
Glycine max - metabolism
Humans
Isoflavones - chemistry
Isoflavones - metabolism
Nutritive Value
Phytoestrogens - chemistry
Phytoestrogens - metabolism
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Summary:Soy, a major component of the diet for centuries contains the largest concentration of isoflavones, a class of phytoestrogens. A variety of health benefits are associated with the consumption of soy primarily because of the isoflavones genistein, daidzein, and glycitein with a potential protective effect against a number of chronic diseases. Owing to the pharmaceutical and nutraceutical properties allied with isoflavonoids and their use in functional foods, there is a growing interest in these compounds. This review throws light on the chemistry, and significant pharmacological and biopharmaceutical aspects of soy isoflavones. This article critically describes the mechanisms of action, infers conclusions and shows opportunity for future research.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1701200439