The role of silent helicobacter pylori infection in intragastric ulcers induced by balloon insertion used for management of obesity

• Published in: Diabetes & metabolic syndrome clinical research & reviews 2019-01, Vol.13 (1), p.116-121
• Main Authors: Haydara, Tamer, Kabel, Ahmed M., Elsaka, Ayman M.
• Format: Article
• Language: English
• Subjects: Helicobacter pylori; Intragastric balloon; Obesity; Ulcers
• ISSN: 1871-4021; 1878-0334
• DOI: 10.1016/j.dsx.2018.08.023

Obesity represents one of the common medical disorders that carries a high risk of morbidity and mortality. Insertion of intragastric balloon is one of the recently introduced lines of treatment of obesity. It allows patients to sense abdominal fullness and reduce their food intake. However, gastric ulceration may be a serious adverse effect that may be associated with intragastric balloon insertion. To assess the role of silent helicobacter pylori infection in intragastric balloon-induced ulcers and to explore the possible methods for amelioration of this effect. Thirty patients were divided into 2 equal groups; one of them received triple therapy for helicobacter pylori eradication and the other group received placebo treatment. Then, they underwent intragastric balloon insertion. After removal of the balloon, gastroscopy was performed to evaluate the gastric mucosal lesions, if present. There was significant decrease in the incidence of gastric erosions and ulcerations in the group that received triple therapy for helicobacter pylori eradication compared to the group that received placebo treatment. Eradication of silent helicobacter pylori infection may represent a promising hope to decrease the incidence and improve symptoms of gastric erosions and ulceration that may be associated with intragastric balloon insertion.