Physiology of puberty in boys and girls and pathological disorders affecting its onset

Puberty is a physiological event involving the attainment of reproductive capability and complete development of sexual and physical organs. Changing from childhood to adulthood is a complex process and is tightly controlled by interconnection pathways at the level of the hypothalamus which can be i...

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Bibliographic Details
Published in:Journal of adolescence (London, England.) England.), 2019-02, Vol.71 (1), p.63-71
Main Author: Alotaibi, Mohammed F.
Format: Article
Language:English
Subjects:
Adolescent
Adolescent boys
Boys
Childhood
Children
Disorders
Disorders of Sex Development - physiopathology
Female
Girls
Hormones
Humans
Male
Physiology
Psychosocial factors
Puberty
Puberty - physiology
Sex Characteristics
Sexual Maturation - physiology
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Summary:Puberty is a physiological event involving the attainment of reproductive capability and complete development of sexual and physical organs. Changing from childhood to adulthood is a complex process and is tightly controlled by interconnection pathways at the level of the hypothalamus which can be influenced by environmental, psychosocial, and endocrine factors. Although various mechanisms underlying the onset of normal puberty have been investigated in humans and animals, the exact molecular mechanisms thereof remain unclear. The aim of this review is to summarize the current state of knowledge and provide a synoptic overview about the physiology of puberty in adolescent boys and girls, and describe pathological disorders affecting its onset.
ISSN:0140-1971
1095-9254
DOI:10.1016/j.adolescence.2018.12.007