Statistical Analysis Plan for “An international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery”

• Published in: Pediatric anesthesia 2019-03, Vol.29 (3), p.243-249
• Main Authors: Yuan, Ian, Olbrecht, Vanessa A., Mensinger, Janell L., Zhang, Bingqing, Davidson, Andrew J., von Ungern‐Sternberg, Britta S., Skowno, Justin, Lian, QingQuan, Song, XingRong, Zhao, Pin, Zhang, JianMin, Zhang, MaZhong, Zuo, YunXia, de Graaff, Jurgen C., Vutskits, Laszlo, Szmuk, Peter, Kurth, Charles D., Anderson, Brian
• Format: Article
• Language: English
• Subjects: EEG; Electroencephalography; isoelectric EEG; SAP; SAP example; SAP template; Statistical analysis; Statistical Analysis Plan
• ISSN: 1155-5645; 1460-9592
• DOI: 10.1111/pan.13589

Summary This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study. It consists of a basic description of the study in broad terms and separate sections that detail the methods of different aspects of the statistical analysis, summarized under the following headings (a) Background; (b) Definitions of protocol violations; (c) Definitions of objectives and other terms; (d) Variables for analyses; (e) Handling of missing data and study bias; (f) Statistical analysis of the primary and secondary study outcomes; (g) Reporting of study results; and (h) References. It serves as a template for researchers interested in writing a Statistical Analysis Plan.