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A new thiodiketopiperzaine from the marine sponge Tedania sp

A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiket...

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Published in:Natural product research 2020-04, Vol.34 (8), p.1113-1117
Main Authors: Zhang, Hua, Lai, Wei, Guan, Zhuo-Bin, Liao, Xiao-Jian, Zhao, Bing-Xin, Xu, Shi-Hai
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Language:English
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cited_by cdi_FETCH-LOGICAL-c441t-fe541cf97d87e941dd76d6720851ae038cf2f79ba9cb44240307f8ed906ab4a63
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creator Zhang, Hua
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description A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiketopiperazine bearing a thiazolidine unit. Cytotoxic activities of 1 were also evaluated.
doi_str_mv 10.1080/14786419.2018.1550770
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subjects Absolute configuration
Animals
Cell Line
Cytotoxicity
Cytotoxins - chemistry
Cytotoxins - isolation & purification
Cytotoxins - pharmacology
Diketopiperazines - chemistry
Diketopiperazines - isolation & purification
Diketopiperazines - pharmacology
Humans
Molecular Conformation
Molecular Structure
Porifera - chemistry
Spectrum Analysis
Sponge
Tedania
Tedania sp
Thiazoles - chemistry
Thiazoles - isolation & purification
Thiazoles - pharmacology
thiodiketopiperzaine
title A new thiodiketopiperzaine from the marine sponge Tedania sp
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