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A new thiodiketopiperzaine from the marine sponge Tedania sp
A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiket...
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Published in: | Natural product research 2020-04, Vol.34 (8), p.1113-1117 |
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creator | Zhang, Hua Lai, Wei Guan, Zhuo-Bin Liao, Xiao-Jian Zhao, Bing-Xin Xu, Shi-Hai |
description | A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiketopiperazine bearing a thiazolidine unit. Cytotoxic activities of 1 were also evaluated. |
doi_str_mv | 10.1080/14786419.2018.1550770 |
format | article |
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subjects | Absolute configuration Animals Cell Line Cytotoxicity Cytotoxins - chemistry Cytotoxins - isolation & purification Cytotoxins - pharmacology Diketopiperazines - chemistry Diketopiperazines - isolation & purification Diketopiperazines - pharmacology Humans Molecular Conformation Molecular Structure Porifera - chemistry Spectrum Analysis Sponge Tedania Tedania sp Thiazoles - chemistry Thiazoles - isolation & purification Thiazoles - pharmacology thiodiketopiperzaine |
title | A new thiodiketopiperzaine from the marine sponge Tedania sp |
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