Aspirin for Primary Prevention: Clinical Considerations in 2019

Reducing platelet activity with aspirin and other antiplatelet agents is an important factor in the prevention and management of atherothrombotic vascular events. For this indication, aspirin has both beneficial and potentially harmful effects; it can diminish or reverse thrombus formation (eg, in t...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2019-01, Vol.321 (3), p.253-255
Main Author: Gaziano, J. Michael
Format: Article
Language:English
Subjects:
Antiplatelet therapy
Aspirin
Bleeding
Cerebral infarction
Disease prevention
Hemorrhage
Humans
Myocardial infarction
Prevention
Primary Prevention
Risk assessment
Thrombosis
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Description
Summary:Reducing platelet activity with aspirin and other antiplatelet agents is an important factor in the prevention and management of atherothrombotic vascular events. For this indication, aspirin has both beneficial and potentially harmful effects; it can diminish or reverse thrombus formation (eg, in the setting of acute myocardial infarction or stroke), but it also increases the risk of bleeding.
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2018.20577