Analyte-Tailored Controlled Atmosphere Improves Dielectric Barrier Discharge Ionization Mass Spectrometry Performance

Plasma sources in atmospheric pressure soft-ionization mass spectrometry have gained significant interest in recent years. As many of these sources are used under ambient air conditions, their interaction with the surrounding atmosphere plays an important role in the ionization pathway. This study f...

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Bibliographic Details
Published in:Analytical chemistry (Washington) 2019-03, Vol.91 (5), p.3733-3739
Main Authors: Vogel, Pascal, Marggraf, Ulrich, Brandt, Sebastian, García-Reyes, Juan F, Franzke, Joachim
Format: Article
Language:English
Subjects:
Atmosphere
Chemistry
Dielectric barrier discharge
Gas mixtures
Gases
Ionization
Ions
Mass spectrometry
Mass spectroscopy
Perfluoro compounds
Plasma
Scientific imaging
Spectroscopy
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Summary:Plasma sources in atmospheric pressure soft-ionization mass spectrometry have gained significant interest in recent years. As many of these sources are used under ambient air conditions, their interaction with the surrounding atmosphere plays an important role in the ionization pathway. This study focuses on the interaction between the plasma source and the surrounding atmosphere by connecting the plasma source to the mass spectrometer using a 2 mm ID closed reactant capillary supplied by a reactant gas up to 500 mL per minute to gain a controlled atmosphere. Different reactant gases (Ar, He, O2, and N2) and reactant gas mixtures are tested with regard to the DBDI performance and then used to improve the ionization efficiency. Tailoring the controlled atmosphere for a certain analyte, for example, perfluorinated compounds, leads to significantly improved limits of detection up to 2 ppb.
ISSN:0003-2700
1520-6882
DOI:10.1021/acs.analchem.9b00112