Guidance of sentinel lymph node biopsy decisions in patients with T1-T2 melanoma using gene expression profiling

Can gene expression profiling be used to identify patients with T1-T2 melanoma at low risk for sentinel lymph node (SLN) positivity? Bioinformatics modeling determined a population in which a 31-gene expression profile test predicted

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Bibliographic Details
Published in:Future oncology (London, England) England), 2019-04, Vol.15 (11), p.1207-1217
Main Authors: Vetto, John T, Hsueh, Eddy C, Gastman, Brian R, Dillon, Larry D, Monzon, Federico A, Cook, Robert W, Keller, Jennifer, Huang, Xin, Fleming, Andrew, Hewgley, Preston, Gerami, Pedram, Leachman, Sancy, Wayne, Jeffrey D, Berger, Adam C, Fleming, Martin D
Format: Article
Language:English
Subjects:
Age
biomarker
Biopsy
Decision making
Gene expression
gene expression profiling
Lymphatic system
Medical prognosis
Melanoma
Metastasis
Patients
prognosis
sentinel lymph node biopsy
Skin cancer
Studies
Thyroid gland
Tumors
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Description
Summary:Can gene expression profiling be used to identify patients with T1-T2 melanoma at low risk for sentinel lymph node (SLN) positivity? Bioinformatics modeling determined a population in which a 31-gene expression profile test predicted
ISSN:1479-6694
1744-8301
DOI:10.2217/fon-2018-0912