Differentiating bipolar disorder from borderline personality disorder: Diagnostic accuracy of the difficulty in emotion regulation scale and personality inventory for DSM-5

•Personality traits differentiate bipolar disorder (BD) from borderline personality disorder (BPD) patients.•PID-5 traits of emotional lability, anxiousness, separation insecurity, hostility, depressivity, impulsivity, and risk taking provided good specificity (SP = 0.79) and sensitivity (SN = 0.77)...

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Bibliographic Details
Published in:Journal of affective disorders 2019-02, Vol.245, p.856-860
Main Authors: Fowler, J Christopher, Madan, Alok, Allen, Jon G, Oldham, John M, Frueh, B Christopher
Format: Article
Language:English
Subjects:
Adult
Algorithms
Bipolar disorder
Bipolar Disorder - diagnosis
Bipolar Disorder - psychology
Borderline personality disorder
Borderline Personality Disorder - diagnosis
Borderline Personality Disorder - psychology
Diagnosis, Differential
Diagnostic and Statistical Manual of Mental Disorders
Diagnostic test
Emotion dysregulation
Emotions
Female
Humans
Male
Middle Aged
Personality Inventory
Reproducibility of Results
ROC Curve
Self Report
Young Adult
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Summary:•Personality traits differentiate bipolar disorder (BD) from borderline personality disorder (BPD) patients.•PID-5 traits of emotional lability, anxiousness, separation insecurity, hostility, depressivity, impulsivity, and risk taking provided good specificity (SP = 0.79) and sensitivity (SN = 0.77).•Self-report measure of emotion dysregulation was marginally successful in differentiating BD from BPD patients.•Tools that make complex differential diagnosis more accurate have important downstream benefit to patients. Confusion abounds when differentiating the diagnoses of bipolar disorder (BD) from borderline personality disorder (BPD). This study explored the relative clinical utility of affective instability and self-report personality trait measures for accurate identification of BD and BPD. Receiver operator characteristics and diagnostic efficiency statistics were calculated to ascertain the relative diagnostic efficiency of self-report measures. Inpatients with research-confirmed diagnoses of BD (n = 341) or BPD (n = 381) completed the Difficulty in Emotion Regulation Scale (DERS) and Personality Inventory for DSM-5 (PID-5). The total score for DERS evidenced relatively poor accuracy for differentiating the disorders (AUC = 0.72, SE = 0.02, p 
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2018.11.079