Liquid chromatography–mass spectrometry identification of serum biomarkers for nocturia in aged men

Purpose We aimed to investigate the association between nocturia and serum metabolites identified using metabolomics analysis. Methods This study enrolled 66 men aged 65–80 years, recruited from the outpatient department of a university hospital. The participants were stratified as follows: Nocturia...

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Bibliographic Details
Published in:World journal of urology 2019-10, Vol.37 (10), p.2199-2205
Main Authors: Kira, Satoru, Mitsui, Takahiko, Miyamoto, Tatsuya, Ihara, Tatsuya, Nakagomi, Hiroshi, Hashimoto, Yuka, Takamatsu, Hajime, Tanahashi, Masayuki, Takeda, Masahiro, Sawada, Norifumi, Andersson, Karl-Erik, Takeda, Masayuki
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Arachidonic acid
Biomarkers
Biomarkers - blood
Cannabinoids
Chromatography
Chromatography, Liquid
Eicosapentaenoic acid
Humans
Liquid chromatography
Male
Mass Spectrometry
Mass spectroscopy
Medicine
Medicine & Public Health
Metabolites
Metabolomics
Multivariate analysis
Nephrology
Nocturia - blood
Nocturnal
Oncology
Original Article
Palmitoylethanolamide
Polyunsaturated fatty acids
Prospective Studies
Prostate
Scientific imaging
Urination
Urine
Urology
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Summary:Purpose We aimed to investigate the association between nocturia and serum metabolites identified using metabolomics analysis. Methods This study enrolled 66 men aged 65–80 years, recruited from the outpatient department of a university hospital. The participants were stratified as follows: Nocturia group [45 men with any total international prostate symptom score (IPSS) and an average of 3 nights ≥ 1.5 micturitions/night] and Control group (21 men with total IPSS 
ISSN:0724-4983
1433-8726
DOI:10.1007/s00345-019-02647-4