Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: Case report of a rare lesion with novel genetic mutation

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a rare primary cancer of the thyroid. This tumor is analogous to other primary tumors of the salivary glands, breast, pancreas, and esophagus. We present a case of this rare tumor with characteristic clinical features, ultrasound image...

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Bibliographic Details
Published in:Diagnostic cytopathology 2019-06, Vol.47 (6), p.589-593
Main Authors: Wiles, Austin Blackburn, Kraft, Adele O., Mueller, Sandra M., Powers, Celeste N.
Format: Article
Language:English
Subjects:
Biopsy
Blood diseases
carcinoma
Carcinoma, Mucoepidermoid - diagnostic imaging
Carcinoma, Mucoepidermoid - genetics
Carcinoma, Mucoepidermoid - pathology
Case reports
Cytopathology
Eosinophilia
Eosinophilia - diagnostic imaging
Eosinophilia - genetics
Eosinophilia - pathology
Esophagus
Female
Histopathology
Humans
Middle Aged
molecular
mucoepidermoid
Mutation
Mutation - genetics
Pancreas
Point mutation
Salivary gland
Salivary glands
sclerosing
thyroid
Thyroid cancer
Thyroid gland
Thyroid Gland - diagnostic imaging
Thyroid Gland - pathology
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - genetics
Thyroid Neoplasms - pathology
Tumors
ultrasound
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Description
Summary:Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a rare primary cancer of the thyroid. This tumor is analogous to other primary tumors of the salivary glands, breast, pancreas, and esophagus. We present a case of this rare tumor with characteristic clinical features, ultrasound images, cytopathology, histopathology, and a heretofore undocumented somatic gene mutation. Additionally, we provide a succinct review of the controversial literature for this uncommon lesion.
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.24148