Relation between pregestational obesity and characteristics of the placenta

Objective: To evaluate the morphology of the placenta in patients with pregestational overweight (OW), pregestational obesity (PGOB), or normal weight. Methods: A cross-sectional study including women (n = 114) ≥20 years of age with a singleton pregnancy was carried out. The groups were integrated a...

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Published in:The journal of maternal-fetal & neonatal medicine 2020-10, Vol.33 (20), p.3425-3430
Main Authors: Rosado-Yépez, Paola I., Chávez-Corral, Dora V., Reza-López, Sandra A., Leal-Berumen, Irene, Fierro-Murga, Ricardo, Caballero-Cummings, Selene, Levario-Carrillo, Margarita
Format: Article
Language:English
Subjects:
Maternal obesity
placental maturity
placental morphology
placental pathology
placental weight
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Summary:Objective: To evaluate the morphology of the placenta in patients with pregestational overweight (OW), pregestational obesity (PGOB), or normal weight. Methods: A cross-sectional study including women (n = 114) ≥20 years of age with a singleton pregnancy was carried out. The groups were integrated according to pregestational body mass index (BMI): 51 patients had a normal BMI (18.5-24.99 kg/m 2 ), 30 were overweight (25-29.99 kg/m 2 ), and 33 women were obese (≥30.0 kg/m 2 ). A morphometric study of the placenta was performed and the placental maturity index (PMI) was calculated according to the formula: PMI = number of vasculo-syncytial membranes (VSM) in 1 mm 2 /VSM thickness. In the histopathological study, the presence of infarcts, calcifications, hemorrhage, thrombosis, fibrosis, cysts, and edema was determined. Results: The weight and length of newborns at birth were greater in the group with PGOB (p 
ISSN:1476-7058
1476-4954
DOI:10.1080/14767058.2019.1573222