Genetic polymorphism of 27 X-chromosomal short tandem repeats in an Egyptian population

•Population data of 27 X-STR in an Egyptian population are presented.•Allele distributions reflected anthropological history.•Two adjacent pairs of loci showed significant linkage disequilibrium. We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS...

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Bibliographic Details
Published in:Legal medicine (Tokyo, Japan) Japan), 2019-03, Vol.37, p.64-66
Main Authors: Fukuta, Mamiko, Gaballah, Mohammed, Takada, Kazushi, Miyazaki, Hiroki, Kato, Hideaki, Aoki, Yasuhiro, Hamed, Sameera Sh, ElMorsi, Doaa A.A., ElDakroory, Sahar A.
Format: Article
Language:English
Subjects:
Egypt
Short tandem repeats (STR)
X-chromosome
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Summary:•Population data of 27 X-STR in an Egyptian population are presented.•Allele distributions reflected anthropological history.•Two adjacent pairs of loci showed significant linkage disequilibrium. We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS6810, DXS10076, DXS10077, DXS10078, DXS10162, DXS10163, DXS10164, DXS7132, DXS981, DXS6800, DXS6803, DXS6809, DXS6789, DXS6799, DXS7424, DXS101, DXS7133, GATA172D05, DXS10103, HPRTB, GATA31E08, DXS8377, DXS10147, and DXS7423) obtained from 352 unrelated individuals in Egypt. No deviation from Hardy-Weinberg equilibrium was detected. Two pairs of adjacent loci showed significant linkage disequilibrium. In the principal component analysis plot, the Egyptian data were located between Europe and sub-Saharan Africa, away from Asia.
ISSN:1344-6223
1873-4162
DOI:10.1016/j.legalmed.2019.01.009