Genetic polymorphism of 27 X-chromosomal short tandem repeats in an Egyptian population

•Population data of 27 X-STR in an Egyptian population are presented.•Allele distributions reflected anthropological history.•Two adjacent pairs of loci showed significant linkage disequilibrium. We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS...

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Published in:Legal medicine (Tokyo, Japan) Japan), 2019-03, Vol.37, p.64-66
Main Authors: Fukuta, Mamiko, Gaballah, Mohammed, Takada, Kazushi, Miyazaki, Hiroki, Kato, Hideaki, Aoki, Yasuhiro, Hamed, Sameera Sh, ElMorsi, Doaa A.A., ElDakroory, Sahar A.
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Egypt
Short tandem repeats (STR)
X-chromosome
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container_title Legal medicine (Tokyo, Japan)
container_volume 37
creator Fukuta, Mamiko
Gaballah, Mohammed
Takada, Kazushi
Miyazaki, Hiroki
Kato, Hideaki
Aoki, Yasuhiro
Hamed, Sameera Sh
ElMorsi, Doaa A.A.
ElDakroory, Sahar A.
description •Population data of 27 X-STR in an Egyptian population are presented.•Allele distributions reflected anthropological history.•Two adjacent pairs of loci showed significant linkage disequilibrium. We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS6810, DXS10076, DXS10077, DXS10078, DXS10162, DXS10163, DXS10164, DXS7132, DXS981, DXS6800, DXS6803, DXS6809, DXS6789, DXS6799, DXS7424, DXS101, DXS7133, GATA172D05, DXS10103, HPRTB, GATA31E08, DXS8377, DXS10147, and DXS7423) obtained from 352 unrelated individuals in Egypt. No deviation from Hardy-Weinberg equilibrium was detected. Two pairs of adjacent loci showed significant linkage disequilibrium. In the principal component analysis plot, the Egyptian data were located between Europe and sub-Saharan Africa, away from Asia.
doi_str_mv 10.1016/j.legalmed.2019.01.009
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subjects Egypt
Short tandem repeats (STR)
X-chromosome
title Genetic polymorphism of 27 X-chromosomal short tandem repeats in an Egyptian population
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