Hepatitis A immunity in Yozgat, Turkey

Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey. The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age a...

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Bibliographic Details
Published in:Annals of Saudi medicine 2019-01, Vol.39 (1), p.37
Main Authors: Kader, Çigdem, Göçmen, Ayse Yesim, Demir, Münire Islak, Çolak, Nuriye Yalçin, Gök, Sebnem Eren, Arkan, Fatma Inci, Sara, Mehmet Yldrm, Erbay, Ayse
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
Female
Hepatitis A - epidemiology
Hepatitis A - prevention & control
Hepatitis A - virology
Hepatitis A Antibodies - blood
Hepatitis A Vaccines - therapeutic use
Hepatitis A virus - immunology
Humans
Male
Middle Aged
Seroepidemiologic Studies
Turkey - epidemiology
Vaccination - statistics & numerical data
Young Adult
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Summary:Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey. The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey. Cross-sectional. Community in central region of Turkey. Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA. The rates of hepatitis A immunity by age group. 1862. Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001). A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat. Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended. None.
ISSN:0975-4466
0975-4466
DOI:10.5144/0256.4947.2019.37