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Hepatitis A immunity in Yozgat, Turkey
Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey. The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age a...
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Published in: | Annals of Saudi medicine 2019-01, Vol.39 (1), p.37 |
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container_title | Annals of Saudi medicine |
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creator | Kader, Çigdem Göçmen, Ayse Yesim Demir, Münire Islak Çolak, Nuriye Yalçin Gök, Sebnem Eren Arkan, Fatma Inci Sara, Mehmet Yldrm Erbay, Ayse |
description | Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey.
The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey.
Cross-sectional.
Community in central region of Turkey.
Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA.
The rates of hepatitis A immunity by age group.
1862.
Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001).
A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat.
Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended.
None. |
doi_str_mv | 10.5144/0256.4947.2019.37 |
format | article |
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The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey.
Cross-sectional.
Community in central region of Turkey.
Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA.
The rates of hepatitis A immunity by age group.
1862.
Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001).
A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat.
Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended.
None.</description><identifier>ISSN: 0975-4466</identifier><identifier>EISSN: 0975-4466</identifier><identifier>DOI: 10.5144/0256.4947.2019.37</identifier><identifier>PMID: 30712049</identifier><language>eng</language><publisher>Saudi Arabia</publisher><subject>Adolescent ; Adult ; Child ; Cross-Sectional Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Hepatitis A - epidemiology ; Hepatitis A - prevention & control ; Hepatitis A - virology ; Hepatitis A Antibodies - blood ; Hepatitis A Vaccines - therapeutic use ; Hepatitis A virus - immunology ; Humans ; Male ; Middle Aged ; Seroepidemiologic Studies ; Turkey - epidemiology ; Vaccination - statistics & numerical data ; Young Adult</subject><ispartof>Annals of Saudi medicine, 2019-01, Vol.39 (1), p.37</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30712049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kader, Çigdem</creatorcontrib><creatorcontrib>Göçmen, Ayse Yesim</creatorcontrib><creatorcontrib>Demir, Münire Islak</creatorcontrib><creatorcontrib>Çolak, Nuriye Yalçin</creatorcontrib><creatorcontrib>Gök, Sebnem Eren</creatorcontrib><creatorcontrib>Arkan, Fatma Inci</creatorcontrib><creatorcontrib>Sara, Mehmet Yldrm</creatorcontrib><creatorcontrib>Erbay, Ayse</creatorcontrib><title>Hepatitis A immunity in Yozgat, Turkey</title><title>Annals of Saudi medicine</title><addtitle>Ann Saudi Med</addtitle><description>Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey.
The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey.
Cross-sectional.
Community in central region of Turkey.
Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA.
The rates of hepatitis A immunity by age group.
1862.
Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001).
A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat.
Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended.
None.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Child</subject><subject>Cross-Sectional Studies</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Hepatitis A - epidemiology</subject><subject>Hepatitis A - prevention & control</subject><subject>Hepatitis A - virology</subject><subject>Hepatitis A Antibodies - blood</subject><subject>Hepatitis A Vaccines - therapeutic use</subject><subject>Hepatitis A virus - immunology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Seroepidemiologic Studies</subject><subject>Turkey - epidemiology</subject><subject>Vaccination - statistics & numerical data</subject><subject>Young Adult</subject><issn>0975-4466</issn><issn>0975-4466</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpNj71KxEAURgdR3HX1AWwklViYeOffKZdFXWHBJo1VuEluZDTJxkxSxKffgCtYfac4HPgYu-aQaK7UAwhtEuWUTQRwl0h7wpbgrI6VMub0Hy_YRQifAAKUlOdsIcHymd2S3W6pw8EPPkTryDfN2Pphinwbve9_PnC4j9Kx_6Lpkp1VWAe6Ou6Kpc9P6WYb795eXjfrXdxp42KnKwJblgBKyJwqrkDmAslwjiZHUhVoYcxjgWWZ54AEJUluNUc0Ek0hV-zuN9v1---RwpA1PhRU19jSfgyZ4NZpqeferN4c1TFvqMy63jfYT9nfNXkAyYhPBA</recordid><startdate>201901</startdate><enddate>201901</enddate><creator>Kader, Çigdem</creator><creator>Göçmen, Ayse Yesim</creator><creator>Demir, Münire Islak</creator><creator>Çolak, Nuriye Yalçin</creator><creator>Gök, Sebnem Eren</creator><creator>Arkan, Fatma Inci</creator><creator>Sara, Mehmet Yldrm</creator><creator>Erbay, Ayse</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201901</creationdate><title>Hepatitis A immunity in Yozgat, Turkey</title><author>Kader, Çigdem ; Göçmen, Ayse Yesim ; Demir, Münire Islak ; Çolak, Nuriye Yalçin ; Gök, Sebnem Eren ; Arkan, Fatma Inci ; Sara, Mehmet Yldrm ; Erbay, Ayse</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p569-95fe07dd00423bef1403b2ae611a6bae4f052668caddbb0ae0de31751aa63a6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Child</topic><topic>Cross-Sectional Studies</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Hepatitis A - epidemiology</topic><topic>Hepatitis A - prevention & control</topic><topic>Hepatitis A - virology</topic><topic>Hepatitis A Antibodies - blood</topic><topic>Hepatitis A Vaccines - therapeutic use</topic><topic>Hepatitis A virus - immunology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Seroepidemiologic Studies</topic><topic>Turkey - epidemiology</topic><topic>Vaccination - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kader, Çigdem</creatorcontrib><creatorcontrib>Göçmen, Ayse Yesim</creatorcontrib><creatorcontrib>Demir, Münire Islak</creatorcontrib><creatorcontrib>Çolak, Nuriye Yalçin</creatorcontrib><creatorcontrib>Gök, Sebnem Eren</creatorcontrib><creatorcontrib>Arkan, Fatma Inci</creatorcontrib><creatorcontrib>Sara, Mehmet Yldrm</creatorcontrib><creatorcontrib>Erbay, Ayse</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of Saudi medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kader, Çigdem</au><au>Göçmen, Ayse Yesim</au><au>Demir, Münire Islak</au><au>Çolak, Nuriye Yalçin</au><au>Gök, Sebnem Eren</au><au>Arkan, Fatma Inci</au><au>Sara, Mehmet Yldrm</au><au>Erbay, Ayse</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatitis A immunity in Yozgat, Turkey</atitle><jtitle>Annals of Saudi medicine</jtitle><addtitle>Ann Saudi Med</addtitle><date>2019-01</date><risdate>2019</risdate><volume>39</volume><issue>1</issue><spage>37</spage><pages>37-</pages><issn>0975-4466</issn><eissn>0975-4466</eissn><abstract>Since routine immunization could change the epidemiological profile of hepatitis A virus (HAV) infection in the future, it is important to determine the baseline immunity to HAV across Turkey.
The aim of this study was to determine the seroprevalence of hepatitis A among individuals 6 years of age and older in Yozgat, Turkey.
Cross-sectional.
Community in central region of Turkey.
Questionnaires and blood specimens were collected and the presence of hepatitis A IgG antibodies against hepatitis A virus was determined quantitatively by ELISA.
The rates of hepatitis A immunity by age group.
1862.
Immunity to hepatitis A was 79.1% (n=1473). The mean (SD) age was 17.1 (14.7) years in the nonimmune group and 37.8 (19.5) years in the immune group (P less than .001), and immunity increased with age. No significant difference in immunity rate was detected between gen.ders in children and adults. The seropositivity rate for subjects ages 6-19 years was lower than in subjects aged 20-96 years (52.2% versus 93.9%; P less than .001).
A catch-up vaccination program is needed for persons aged 6-19 years in Yozgat.
Single region data which can not be generalized. For this reason, a multi-centered study that can reflect the whole country is recommended.
None.</abstract><cop>Saudi Arabia</cop><pmid>30712049</pmid><doi>10.5144/0256.4947.2019.37</doi></addata></record> |
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subjects | Adolescent Adult Child Cross-Sectional Studies Enzyme-Linked Immunosorbent Assay Female Hepatitis A - epidemiology Hepatitis A - prevention & control Hepatitis A - virology Hepatitis A Antibodies - blood Hepatitis A Vaccines - therapeutic use Hepatitis A virus - immunology Humans Male Middle Aged Seroepidemiologic Studies Turkey - epidemiology Vaccination - statistics & numerical data Young Adult |
title | Hepatitis A immunity in Yozgat, Turkey |
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