Impact of reduced pulmonary function in the Japanese general population: Lessons from the Yamagata-Takahata study

Regional epidemiological studies for respiratory diseases have been rarely performed in Japan, because spirometry is not regularly conducted in the standard annual health checks. The Yamagata-Takahata Study is an epidemiological study utilizing regional characteristics based on the 21st Century Cent...

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Bibliographic Details
Published in:Respiratory investigation 2019-05, Vol.57 (3), p.220-226
Main Authors: Shibata, Yoko, Inoue, Sumito, Watanabe, Masafumi
Format: Article
Language:English
Subjects:
Adiponectin - blood
Asian Continental Ancestry Group - statistics & numerical data
Atrial Fibrillation - epidemiology
Biomarkers - blood
cigarette smoking
Cigarette Smoking - adverse effects
Cigarette Smoking - epidemiology
Comorbidity
Diabetes Mellitus - epidemiology
Female
Homocysteine - blood
Humans
Japan - epidemiology
Lung - physiopathology
Male
Metabolic Syndrome - epidemiology
Physical Examination
Population-based epidemiology
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary Disease, Chronic Obstructive - physiopathology
pulmonary function
Respiratory Function Tests
Risk Factors
Spirometry
Uric Acid - blood
Yamagata-Takahata Study
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Summary:Regional epidemiological studies for respiratory diseases have been rarely performed in Japan, because spirometry is not regularly conducted in the standard annual health checks. The Yamagata-Takahata Study is an epidemiological study utilizing regional characteristics based on the 21st Century Centers of Excellence (COE) Program and the Global COE Program. Spirometric examination and other specific measurements via blood sampling were performed for the study participants in annual health check-ups held in Takahata, a town in Yamagata Prefecture. The Yamagata-Takahata Study revealed the impact of cigarette smoking habit on pulmonary function, the impact of reduced pulmonary function on mortality, and the situation regarding COPD comorbidities in Japan. Additionally, the study identified biomarkers of decline in pulmonary function among active smokers, and the risk factors for respiratory mortality in Japan. In this review, we summarize the findings of the Yamagata-Takahata study regarding the association between lower pulmonary function and the clinical characteristics of a Japanese general population.
ISSN:2212-5345
2212-5353
DOI:10.1016/j.resinv.2019.01.005