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Distribution of peripheral blood lymphocyte subsets in 826 healthy children aged 0-6 years
To study the distribution of peripheral blood lymphocyte subsets in healthy children aged 0-6 years. A total of 826 healthy Han children aged 0-6 years were recruited. According to their age, the children were divided into four groups: newborn, infant, toddler and preschool. Their peripheral blood s...
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| Published in: | Zhongguo dang dai er ke za zhi 2019-02, Vol.21 (2), p.180 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | Chinese |
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| container_issue | 2 |
| container_start_page | 180 |
| container_title | Zhongguo dang dai er ke za zhi |
| container_volume | 21 |
| creator | Zhan, Wen-Li Yang, Xiao-Han Guo, Hao Zhong, Zhi-Cheng DU, Qian-Yi Zhang, Chang-Bin Huang, Bin-Mei Liu, Hong Luo, Ming-Yong |
| description | To study the distribution of peripheral blood lymphocyte subsets in healthy children aged 0-6 years.
A total of 826 healthy Han children aged 0-6 years were recruited. According to their age, the children were divided into four groups: newborn, infant, toddler and preschool. Their peripheral blood samples were collected to measure the percentages of lymphocyte subsets by flow cytometry.
There were significant differences in the percentages of CD3
T cells, CD3
CD4
T cells and CD3
CD19
B cells and the CD4
/CD8
ratio between boys and girls (P |
| doi_str_mv | 10.7499/j.issn.1008-8830.2019.02.015 |
| format | article |
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A total of 826 healthy Han children aged 0-6 years were recruited. According to their age, the children were divided into four groups: newborn, infant, toddler and preschool. Their peripheral blood samples were collected to measure the percentages of lymphocyte subsets by flow cytometry.
There were significant differences in the percentages of CD3
T cells, CD3
CD4
T cells and CD3
CD19
B cells and the CD4
/CD8
ratio between boys and girls (P<0.05). The girls had a lower percentage of CD3
CD19
B cells, higher percentages of CD3
T cells and CD3
CD4
T cells and a higher CD4
/CD8
ratio than the boys. The newborn group had the highest percentages of CD3
T cells and CD3
CD4
T cells and the highest CD4
/CD8
ratio (P<0.05). The percentage of CD3
CD4
T cells and the CD4
/CD8
ratio gradually decreased with age and the preschool group had the lowest values (P<0.05). The newborn group had the lowest percentages of CD3
CD19</description><identifier>ISSN: 1008-8830</identifier><identifier>DOI: 10.7499/j.issn.1008-8830.2019.02.015</identifier><identifier>PMID: 30782284</identifier><language>chi</language><publisher>China</publisher><subject>Antigens, CD19 ; B-Lymphocytes ; Child ; Child, Preschool ; Female ; Flow Cytometry ; Humans ; Infant ; Infant, Newborn ; Killer Cells, Natural ; Lymphocyte Count ; Lymphocyte Subsets ; Male</subject><ispartof>Zhongguo dang dai er ke za zhi, 2019-02, Vol.21 (2), p.180</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30782284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhan, Wen-Li</creatorcontrib><creatorcontrib>Yang, Xiao-Han</creatorcontrib><creatorcontrib>Guo, Hao</creatorcontrib><creatorcontrib>Zhong, Zhi-Cheng</creatorcontrib><creatorcontrib>DU, Qian-Yi</creatorcontrib><creatorcontrib>Zhang, Chang-Bin</creatorcontrib><creatorcontrib>Huang, Bin-Mei</creatorcontrib><creatorcontrib>Liu, Hong</creatorcontrib><creatorcontrib>Luo, Ming-Yong</creatorcontrib><title>Distribution of peripheral blood lymphocyte subsets in 826 healthy children aged 0-6 years</title><title>Zhongguo dang dai er ke za zhi</title><addtitle>Zhongguo Dang Dai Er Ke Za Zhi</addtitle><description>To study the distribution of peripheral blood lymphocyte subsets in healthy children aged 0-6 years.
A total of 826 healthy Han children aged 0-6 years were recruited. According to their age, the children were divided into four groups: newborn, infant, toddler and preschool. Their peripheral blood samples were collected to measure the percentages of lymphocyte subsets by flow cytometry.
There were significant differences in the percentages of CD3
T cells, CD3
CD4
T cells and CD3
CD19
B cells and the CD4
/CD8
ratio between boys and girls (P<0.05). The girls had a lower percentage of CD3
CD19
B cells, higher percentages of CD3
T cells and CD3
CD4
T cells and a higher CD4
/CD8
ratio than the boys. The newborn group had the highest percentages of CD3
T cells and CD3
CD4
T cells and the highest CD4
/CD8
ratio (P<0.05). The percentage of CD3
CD4
T cells and the CD4
/CD8
ratio gradually decreased with age and the preschool group had the lowest values (P<0.05). The newborn group had the lowest percentages of CD3
CD19</description><subject>Antigens, CD19</subject><subject>B-Lymphocytes</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Flow Cytometry</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Killer Cells, Natural</subject><subject>Lymphocyte Count</subject><subject>Lymphocyte Subsets</subject><subject>Male</subject><issn>1008-8830</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNo9kL1OwzAYRT2AaCm8AvLAwJLw-SeOPaLyK1VigYUlcpLPxJWbBDsZ8vYgUZiOdHV0h0PINYO8lMbc7nOfUp8zAJ1pLSDnwEwOPAdWnJD1_74i5yntAQotjTgjKwGl5lzLNfm492mKvp4nP_R0cHTE6McOow20DsPQ0rAcxm5olglpmuuEU6K-p5or2qENU7fQpvOhjdhT-4kthUzRBW1MF-TU2ZDw8sgNeX98eNs-Z7vXp5ft3S4bGVdTZqBEJ5hxRmjWWCNcKzVT2PJSMSUEglPC8lo6hiBEAS3W1pUFKxpVOFeKDbn5_R3j8DVjmqqDTw2GYHsc5lRxpiWTAEL-qFdHda4P2FZj9Acbl-qvh_gGzvhjBg</recordid><startdate>201902</startdate><enddate>201902</enddate><creator>Zhan, Wen-Li</creator><creator>Yang, Xiao-Han</creator><creator>Guo, Hao</creator><creator>Zhong, Zhi-Cheng</creator><creator>DU, Qian-Yi</creator><creator>Zhang, Chang-Bin</creator><creator>Huang, Bin-Mei</creator><creator>Liu, Hong</creator><creator>Luo, Ming-Yong</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201902</creationdate><title>Distribution of peripheral blood lymphocyte subsets in 826 healthy children aged 0-6 years</title><author>Zhan, Wen-Li ; Yang, Xiao-Han ; Guo, Hao ; Zhong, Zhi-Cheng ; DU, Qian-Yi ; Zhang, Chang-Bin ; Huang, Bin-Mei ; Liu, Hong ; Luo, Ming-Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-907ef319f9381ca93fd4816ed2761633e0f63a2b4f1e03350debaf7515c65ff73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2019</creationdate><topic>Antigens, CD19</topic><topic>B-Lymphocytes</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Flow Cytometry</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Killer Cells, Natural</topic><topic>Lymphocyte Count</topic><topic>Lymphocyte Subsets</topic><topic>Male</topic><toplevel>online_resources</toplevel><creatorcontrib>Zhan, Wen-Li</creatorcontrib><creatorcontrib>Yang, Xiao-Han</creatorcontrib><creatorcontrib>Guo, Hao</creatorcontrib><creatorcontrib>Zhong, Zhi-Cheng</creatorcontrib><creatorcontrib>DU, Qian-Yi</creatorcontrib><creatorcontrib>Zhang, Chang-Bin</creatorcontrib><creatorcontrib>Huang, Bin-Mei</creatorcontrib><creatorcontrib>Liu, Hong</creatorcontrib><creatorcontrib>Luo, Ming-Yong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhongguo dang dai er ke za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhan, Wen-Li</au><au>Yang, Xiao-Han</au><au>Guo, Hao</au><au>Zhong, Zhi-Cheng</au><au>DU, Qian-Yi</au><au>Zhang, Chang-Bin</au><au>Huang, Bin-Mei</au><au>Liu, Hong</au><au>Luo, Ming-Yong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Distribution of peripheral blood lymphocyte subsets in 826 healthy children aged 0-6 years</atitle><jtitle>Zhongguo dang dai er ke za zhi</jtitle><addtitle>Zhongguo Dang Dai Er Ke Za Zhi</addtitle><date>2019-02</date><risdate>2019</risdate><volume>21</volume><issue>2</issue><spage>180</spage><pages>180-</pages><issn>1008-8830</issn><abstract>To study the distribution of peripheral blood lymphocyte subsets in healthy children aged 0-6 years.
A total of 826 healthy Han children aged 0-6 years were recruited. According to their age, the children were divided into four groups: newborn, infant, toddler and preschool. Their peripheral blood samples were collected to measure the percentages of lymphocyte subsets by flow cytometry.
There were significant differences in the percentages of CD3
T cells, CD3
CD4
T cells and CD3
CD19
B cells and the CD4
/CD8
ratio between boys and girls (P<0.05). The girls had a lower percentage of CD3
CD19
B cells, higher percentages of CD3
T cells and CD3
CD4
T cells and a higher CD4
/CD8
ratio than the boys. The newborn group had the highest percentages of CD3
T cells and CD3
CD4
T cells and the highest CD4
/CD8
ratio (P<0.05). The percentage of CD3
CD4
T cells and the CD4
/CD8
ratio gradually decreased with age and the preschool group had the lowest values (P<0.05). The newborn group had the lowest percentages of CD3
CD19</abstract><cop>China</cop><pmid>30782284</pmid><doi>10.7499/j.issn.1008-8830.2019.02.015</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1008-8830 |
| ispartof | Zhongguo dang dai er ke za zhi, 2019-02, Vol.21 (2), p.180 |
| issn | 1008-8830 |
| language | chi |
| recordid | cdi_proquest_miscellaneous_2184140034 |
| source | PubMed Central |
| subjects | Antigens, CD19 B-Lymphocytes Child Child, Preschool Female Flow Cytometry Humans Infant Infant, Newborn Killer Cells, Natural Lymphocyte Count Lymphocyte Subsets Male |
| title | Distribution of peripheral blood lymphocyte subsets in 826 healthy children aged 0-6 years |
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