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An ERK Phosphoproteome Expands Chemotactic Signaling in Dictyostelium

In this issue of Developmental Cell, Nichols et al. (2019) establish the MAP kinase ErkB as a critical component for chemotaxis signaling in Dictyostelium. Using phosphoproteomics, they identify a chemoattractant-dependent ErkB targeted core set of signal transduction proteins, which collectively su...

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Bibliographic Details
Published in:Developmental cell 2019-02, Vol.48 (4), p.421-422
Main Author: Kimmel, Alan R.
Format: Article
Language:English
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Summary:In this issue of Developmental Cell, Nichols et al. (2019) establish the MAP kinase ErkB as a critical component for chemotaxis signaling in Dictyostelium. Using phosphoproteomics, they identify a chemoattractant-dependent ErkB targeted core set of signal transduction proteins, which collectively suggest an added mechanistic pathway for chemotactic regulation. In this issue of Developmental Cell, Nichols et al. (2019) establish the MAP kinase ErkB as a critical component for chemotaxis signaling in Dictyostelium. Using phosphoproteomics, they identify a chemoattractant-dependent ErkB targeted core set of signal transduction proteins, which collectively suggest an added mechanistic pathway for chemotactic regulation.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2019.02.006