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Risk Factors for the Development of Stent-Associated Cholangitis Following Endoscopic Biliary Stent Placement

Background and Aim To elucidate the overall risk and risk factors for developing cholangitis following biliary stent placement by endoscopic retrograde cholangiopancreatography (ERCP) and to determine the clinical outcomes of these individuals. Methods We performed a retrospective review of 796 pati...

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Bibliographic Details
Published in:Digestive diseases and sciences 2019-08, Vol.64 (8), p.2300-2307
Main Authors: Everett, Brendan T., Naud, Shelly, Zubarik, Richard S.
Format: Article
Language:English
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Summary:Background and Aim To elucidate the overall risk and risk factors for developing cholangitis following biliary stent placement by endoscopic retrograde cholangiopancreatography (ERCP) and to determine the clinical outcomes of these individuals. Methods We performed a retrospective review of 796 patients who had undergone 1127 ERCPs with biliary stent placement between 2007 and 2015 at a single tertiary care center. There were 91 episodes of stent-associated cholangitis (SAC) during the study period. Data obtained through the medical records included ERCP indication, patient factors (biliary anatomy, demographics, and comorbidities), stent characteristics (material, length, and design), change in serum bilirubin, stent indwelling time, rates and etiologies of bacteremia, and the mortality rate. Results Those with SAC were more likely to have an anatomic biliary stricture (13.1% vs. 2.3%, p  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-019-05533-6