Delineating the critical role of acid additives in Mn-catalysed C-H bond functionalisation processes

Addition of co-catalytic Cy2NH to Mn-catalysed C-H bond activation reactions suggests that the conjugate acid, Cy2NH2X, influences catalysis. Here, acids are shown to positively influence C-H bond alkenylation catalysis involving alkynes. For certain types of alkynes an acid additive is critical to...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2019-03, Vol.55 (22), p.3211-3214
Main Authors: Hammarback, L Anders, Robinson, Alan, Lynam, Jason M, Fairlamb, Ian J S
Format: Article
Language:English
Subjects:
Acrylates
Additives
Alkynes
Catalysis
Hydrogen bonds
Manganese
Substrates
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Addition of co-catalytic Cy2NH to Mn-catalysed C-H bond activation reactions suggests that the conjugate acid, Cy2NH2X, influences catalysis. Here, acids are shown to positively influence C-H bond alkenylation catalysis involving alkynes. For certain types of alkynes an acid additive is critical to catalysis. In stark contrast, acids retard catalysis involving acrylates. [Cy2NH2]X salts also play a key role in thwarting catalyst degradation to manganese clusters. Our findings enable unreactive substrates to be alkenylated.
ISSN:1359-7345
1364-548X
DOI:10.1039/c9cc00257j