Neurosonological and cognitive screening for evaluation of systemic sclerosis patients

Objective Assessment of cerebrovascular hemodynamics, third ventricle diameter (as a proxy of brain atrophy) by transcranial sonography (TCS), and screening of cognitive performance by the Symbol Digit Modalities Test (SDMT) in systemic sclerosis (SSc) patients. Methods A total of 38 SSc patients re...

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Bibliographic Details
Published in:Clinical rheumatology 2019-07, Vol.38 (7), p.1905-1916
Main Authors: Sakr, B. R., Rabea, R. E., Aboulfotooh, A. M., Kishk, N. A.
Format: Article
Language:English
Subjects:
Adult
Aged
Atrophy
Blood Flow Velocity
Case-Control Studies
Cognition
Cognitive ability
Cognitive Dysfunction - diagnosis
Female
Flow velocity
Hemodynamics
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neuropsychological Tests
Original Article
Rheumatology
Scleroderma
Scleroderma, Systemic - diagnostic imaging
Scleroderma, Systemic - pathology
Scleroderma, Systemic - psychology
Severity of Illness Index
Statistical analysis
Systemic sclerosis
Third Ventricle - diagnostic imaging
Third Ventricle - pathology
Ultrasonography, Doppler, Transcranial
Ventricle
Ventricles (cerebral)
Young Adult
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Summary:Objective Assessment of cerebrovascular hemodynamics, third ventricle diameter (as a proxy of brain atrophy) by transcranial sonography (TCS), and screening of cognitive performance by the Symbol Digit Modalities Test (SDMT) in systemic sclerosis (SSc) patients. Methods A total of 38 SSc patients recruited from the outpatient clinic of the Rheumatology Department, Kasr Alainy Hospital, Cairo University, and 51, age- and sex-matched, healthy controls were included in the study. TCS was used to assess the mean flow velocity (MFV), pulsatility index (PI) of the anterior, middle, and posterior cerebral arteries bilaterally, and to measure the third ventricle diameter as a proxy of brain atrophy. Cognitive impairment was screened using the SDMT. p values
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-019-04468-7