Response of Saos-2 osteoblast-like cells to laser surface texturing, sandblasting and hydroxyapatite coating on CoCrMo alloy surfaces

Cobalt chrome alloys are commonly used in orthopaedic implants where high stiffness and wear resistance are required. This study proposes Laser Surface Texturing (LST) as a cost-effective mean for producing bioinspired surface textures in order to improve the performance of CoCrMo orthopaedic implan...

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Bibliographic Details
Published in:Materials Science & Engineering C 2019-05, Vol.98, p.1005-1013
Main Authors: Batal, Afif, Sammons, Rachel, Dimov, Stefan
Format: Article
Language:English
Subjects:
Alloys
Biocompatibility
Cell proliferation
Cobalt
Cobalt base alloys
Disks
Finishes
Hydroxyapatite
Lasers
Materials science
Morphology
Orthopaedic implants
Orthopedics
Performance enhancement
Protective coatings
Sandblasting
Stiffness
Surface energy
Surface properties
Surgical implants
Texturing
Wear resistance
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Summary:Cobalt chrome alloys are commonly used in orthopaedic implants where high stiffness and wear resistance are required. This study proposes Laser Surface Texturing (LST) as a cost-effective mean for producing bioinspired surface textures in order to improve the performance of CoCrMo orthopaedic implants. Cobalt-chrome alloy disks were modified using three different LST strategies: i) micro-scale texturing using a nanosecond laser source; (ii) micro-scale texturing with an ultrashort laser source and (iii) bioinspired sub-micron scale texturing with an ultrashort laser source. The modified disks were characterized and compared to blasted, hydroxyapatite coated and polished surface finishes. Saos-2 osteoblast-like cells were seeded on the different surfaces and their proliferation and morphology was assessed. The laser modification increases the surface energy of the CoCrMo alloy disks when compared to their untreated counterparts. The bioinspired sub-micron textured surfaces exhibited the highest cell metabolic activity on day 7 of the MTT assay. •Saos-2 osteoblast-like cells’ response was evaluated on laser textured CoCrMo alloy disks•The bio-inspired sub-micron topography exhibited the highest levels of cell metabolic activity on day 7 of the MTT assay•Rougher surfaces promote initial cell adhesion whereas smoother surfaces facilitate growth and proliferation•Surface topography is more significant than surface wettability in terms of biological response
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2019.01.067