Long‐term clinical outcomes in patients with autoimmune hepatitis according to treatment response in Asian country

Background & Aims As surrogate markers for autoimmune hepatitis (AIH), serum alanine aminotransferase (ALT) and immunoglobulin G (IgG) are convenient to measure under immunosuppression. However, the long‐term prognosis of patients who achieve complete biochemical remission (CBR) in comparison wi...

Full description

Saved in:
Bibliographic Details
Published in:Liver international 2019-05, Vol.39 (5), p.985-994
Main Authors: Choi, Jonggi, Choi, Gwang Hyeon, Lee, Danbi, Shim, Ju Hyun, Lim, Young‐Suk, Lee, Han Chu, Chung, Young‐Hwa, Lee, Yung‐Sang, Kim, Kang Mo
Format: Article
Language:English
Subjects:
Alanine
Alanine transaminase
autoimmune hepatitis
biochemical response
Cirrhosis
Hepatitis
Hepatocellular carcinoma
Immunoglobulin G
Immunosuppression
Liver
Liver cirrhosis
Liver transplantation
liver‐related adverse outcomes
Patients
Remission
Risk
Transplantation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background & Aims As surrogate markers for autoimmune hepatitis (AIH), serum alanine aminotransferase (ALT) and immunoglobulin G (IgG) are convenient to measure under immunosuppression. However, the long‐term prognosis of patients who achieve complete biochemical remission (CBR) in comparison with patients who achieve only biochemical remission (BR) is uncertain. Methods A total of 291 patients (89.7% female) diagnosed with AIH were retrospectively reviewed. CBR was defined as normal ALT and IgG levels with immunosuppression, while BR was defined as normal ALT levels. CBR was further divided into early CBR (
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.14082