The risk of mortality among people with type 2 diabetes in Latin America: A systematic review and meta‐analysis of population‐based cohort studies

Summary Type 2 diabetes mellitus (T2DM) is associated with a high mortality risk, although the magnitude of this association remains unknown in Latin America (LA). We aimed to assess the strength of the association between T2DM and all‐cause and cause‐specific mortality in population‐based cohort st...

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Published in:Diabetes/metabolism research and reviews 2019-05, Vol.35 (4), p.e3139-n/a
Main Authors: Carrillo‐Larco, Rodrigo M., Barengo, Noël C., Albitres‐Flores, Leonardo, Bernabe‐Ortiz, Antonio
Format: Article
Language:English
Subjects:
Cardiovascular diseases
Cohort analysis
Cohort Studies
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - mortality
Evidence-based medicine
Health risk assessment
Humans
Latin America
Latin America - epidemiology
Meta-analysis
Mortality
Population studies
Population-based studies
Prevalence
Prognosis
Survival Rate
Systematic review
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Summary:Summary Type 2 diabetes mellitus (T2DM) is associated with a high mortality risk, although the magnitude of this association remains unknown in Latin America (LA). We aimed to assess the strength of the association between T2DM and all‐cause and cause‐specific mortality in population‐based cohort studies in LA. Systematic review and meta‐analysis: inclusion criteria were (1) men and women 18 years old and above with T2DM; (2) study outcomes all‐cause and/or cause‐specific mortality; and (3) using people without T2DM as comparison group. Five databases (Scopus, Medline, Embase, Global Health, and LILACS) were searched. Risk of bias was evaluated with the ROBINS‐I criteria. Initially, there were 979 identified studies, of which 17 were selected for qualitative synthesis; 14 were included in the meta‐analysis (N = 416 821). Self‐reported T2DM showed a pooled relative risk (RR) of 2.49 for all‐causes mortality (I‐squared [I2] = 85.7%, p 
ISSN:1520-7552
1520-7560
DOI:10.1002/dmrr.3139