Loading…
Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis
Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders. To determine the association between HS and MS. A systematic review and meta-analysis...
Saved in:
| Published in: | Actas dermo-sifiliográficas (English ed.) 2019-05, Vol.110 (4), p.279-288 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | eng ; spa |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | 288 |
| container_issue | 4 |
| container_start_page | 279 |
| container_title | Actas dermo-sifiliográficas (English ed.) |
| container_volume | 110 |
| creator | Rodríguez-Zuñiga, M J M García-Perdomo, H A Ortega-Loayza, A G |
| description | Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders.
To determine the association between HS and MS.
A systematic review and meta-analysis of observational studies on HS and MS in adults. We searched MEDLINE, SCOPUS, SCIELO, Google Scholar, Science Direct, and LILACS from the inception of the databases to January 2016. We performed a random effects model meta-analysis for studies reporting adjusted and crude odds ratios (ORs) with 95% CIs. A subgroup analysis was related to the type of HS patient (general patients vs hospital patients) and age group (adults vs children and adults).
Five studies including 3950 HS patients were analyzed. We found that MS was pres-ent in 9.64% of HS patients (OR, 1.82; 95%, CI 1.39-2.25). Studies from tertiary care hospital dermatology clinics (OR, 2.82; 95% CI, 0.58-5.06) reported a greater risk for MS than studies carried out in patients treated outside hospitals (OR, 1.78; 95% CI, 1.34-2.22). Studies that included pediatric populations reported a significant association (OR, 2.10; 95% CI, 1.58-2.62).
Few of the included studies reported adjusted ORs.
HS patients have an increased risk for MS. Clinicians should consider screening HS patients for metabolic risk factors. |
| doi_str_mv | 10.1016/j.ad.2018.10.020 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_2189544410</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2189544410</sourcerecordid><originalsourceid>FETCH-LOGICAL-p126t-6d411969d49729d2fa7b35e3704be490867bc8a06ffac612de5f91dccf6c23503</originalsourceid><addsrcrecordid>eNo90M9LwzAUB_AgiBu6uyfJ0UtrXpKmjbc51AkTwem5pMkrZPSXTbux_96K09P7fuHD9_AIuQYWAwN1t4uNizmDbKox4-yMzCFJs4iDZjOyCGHHGAMOIhFwQWaCZVKBknOyW4bQWm8G3zb0AYcDYkPX3vXGYeMHH-h27Lqxn8DeUNM4-oqDKdrKW7o9Nq5va7ynyymHAetJWfqOe4-HfxuZxlTH4MMVOS9NFXBxupfk8-nxY7WONm_PL6vlJuqAqyFSTgJopZ3UKdeOlyYtRIIiZbJAqVmm0sJmhqmyNFYBd5iUGpy1pbJcJExcktvf3a5vv0YMQ177YLGqTIPtGHIOmU6klPBDb050LGp0edf72vTH_O8_4htW6Wd7</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2189544410</pqid></control><display><type>article</type><title>Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis</title><source>ScienceDirect Journals</source><creator>Rodríguez-Zuñiga, M J M ; García-Perdomo, H A ; Ortega-Loayza, A G</creator><creatorcontrib>Rodríguez-Zuñiga, M J M ; García-Perdomo, H A ; Ortega-Loayza, A G</creatorcontrib><description>Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders.
To determine the association between HS and MS.
A systematic review and meta-analysis of observational studies on HS and MS in adults. We searched MEDLINE, SCOPUS, SCIELO, Google Scholar, Science Direct, and LILACS from the inception of the databases to January 2016. We performed a random effects model meta-analysis for studies reporting adjusted and crude odds ratios (ORs) with 95% CIs. A subgroup analysis was related to the type of HS patient (general patients vs hospital patients) and age group (adults vs children and adults).
Five studies including 3950 HS patients were analyzed. We found that MS was pres-ent in 9.64% of HS patients (OR, 1.82; 95%, CI 1.39-2.25). Studies from tertiary care hospital dermatology clinics (OR, 2.82; 95% CI, 0.58-5.06) reported a greater risk for MS than studies carried out in patients treated outside hospitals (OR, 1.78; 95% CI, 1.34-2.22). Studies that included pediatric populations reported a significant association (OR, 2.10; 95% CI, 1.58-2.62).
Few of the included studies reported adjusted ORs.
HS patients have an increased risk for MS. Clinicians should consider screening HS patients for metabolic risk factors.</description><identifier>EISSN: 1578-2190</identifier><identifier>DOI: 10.1016/j.ad.2018.10.020</identifier><identifier>PMID: 30846164</identifier><language>eng ; spa</language><subject>Adult ; Age Factors ; Child ; Comorbidity ; Hidradenitis Suppurativa - epidemiology ; Hidradenitis Suppurativa - physiopathology ; Hospitalization ; Humans ; Metabolic Syndrome - epidemiology ; Metabolic Syndrome - physiopathology ; Observational Studies as Topic ; Odds Ratio ; Risk ; Tertiary Care Centers</subject><ispartof>Actas dermo-sifiliográficas (English ed.), 2019-05, Vol.110 (4), p.279-288</ispartof><rights>Copyright © 2019 AEDV. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30846164$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rodríguez-Zuñiga, M J M</creatorcontrib><creatorcontrib>García-Perdomo, H A</creatorcontrib><creatorcontrib>Ortega-Loayza, A G</creatorcontrib><title>Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis</title><title>Actas dermo-sifiliográficas (English ed.)</title><addtitle>Actas Dermosifiliogr (Engl Ed)</addtitle><description>Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders.
To determine the association between HS and MS.
A systematic review and meta-analysis of observational studies on HS and MS in adults. We searched MEDLINE, SCOPUS, SCIELO, Google Scholar, Science Direct, and LILACS from the inception of the databases to January 2016. We performed a random effects model meta-analysis for studies reporting adjusted and crude odds ratios (ORs) with 95% CIs. A subgroup analysis was related to the type of HS patient (general patients vs hospital patients) and age group (adults vs children and adults).
Five studies including 3950 HS patients were analyzed. We found that MS was pres-ent in 9.64% of HS patients (OR, 1.82; 95%, CI 1.39-2.25). Studies from tertiary care hospital dermatology clinics (OR, 2.82; 95% CI, 0.58-5.06) reported a greater risk for MS than studies carried out in patients treated outside hospitals (OR, 1.78; 95% CI, 1.34-2.22). Studies that included pediatric populations reported a significant association (OR, 2.10; 95% CI, 1.58-2.62).
Few of the included studies reported adjusted ORs.
HS patients have an increased risk for MS. Clinicians should consider screening HS patients for metabolic risk factors.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Child</subject><subject>Comorbidity</subject><subject>Hidradenitis Suppurativa - epidemiology</subject><subject>Hidradenitis Suppurativa - physiopathology</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Metabolic Syndrome - physiopathology</subject><subject>Observational Studies as Topic</subject><subject>Odds Ratio</subject><subject>Risk</subject><subject>Tertiary Care Centers</subject><issn>1578-2190</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNo90M9LwzAUB_AgiBu6uyfJ0UtrXpKmjbc51AkTwem5pMkrZPSXTbux_96K09P7fuHD9_AIuQYWAwN1t4uNizmDbKox4-yMzCFJs4iDZjOyCGHHGAMOIhFwQWaCZVKBknOyW4bQWm8G3zb0AYcDYkPX3vXGYeMHH-h27Lqxn8DeUNM4-oqDKdrKW7o9Nq5va7ynyymHAetJWfqOe4-HfxuZxlTH4MMVOS9NFXBxupfk8-nxY7WONm_PL6vlJuqAqyFSTgJopZ3UKdeOlyYtRIIiZbJAqVmm0sJmhqmyNFYBd5iUGpy1pbJcJExcktvf3a5vv0YMQ177YLGqTIPtGHIOmU6klPBDb050LGp0edf72vTH_O8_4htW6Wd7</recordid><startdate>201905</startdate><enddate>201905</enddate><creator>Rodríguez-Zuñiga, M J M</creator><creator>García-Perdomo, H A</creator><creator>Ortega-Loayza, A G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201905</creationdate><title>Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis</title><author>Rodríguez-Zuñiga, M J M ; García-Perdomo, H A ; Ortega-Loayza, A G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-6d411969d49729d2fa7b35e3704be490867bc8a06ffac612de5f91dccf6c23503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; spa</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Child</topic><topic>Comorbidity</topic><topic>Hidradenitis Suppurativa - epidemiology</topic><topic>Hidradenitis Suppurativa - physiopathology</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Metabolic Syndrome - physiopathology</topic><topic>Observational Studies as Topic</topic><topic>Odds Ratio</topic><topic>Risk</topic><topic>Tertiary Care Centers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodríguez-Zuñiga, M J M</creatorcontrib><creatorcontrib>García-Perdomo, H A</creatorcontrib><creatorcontrib>Ortega-Loayza, A G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Actas dermo-sifiliográficas (English ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rodríguez-Zuñiga, M J M</au><au>García-Perdomo, H A</au><au>Ortega-Loayza, A G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis</atitle><jtitle>Actas dermo-sifiliográficas (English ed.)</jtitle><addtitle>Actas Dermosifiliogr (Engl Ed)</addtitle><date>2019-05</date><risdate>2019</risdate><volume>110</volume><issue>4</issue><spage>279</spage><epage>288</epage><pages>279-288</pages><eissn>1578-2190</eissn><abstract>Recent studies have shown a relationship between hidradenitis suppurativa (HS) and metabolic syndrome (MS), but the literature offers no meta-analysis restricted to studies that have been adjusted for confounders.
To determine the association between HS and MS.
A systematic review and meta-analysis of observational studies on HS and MS in adults. We searched MEDLINE, SCOPUS, SCIELO, Google Scholar, Science Direct, and LILACS from the inception of the databases to January 2016. We performed a random effects model meta-analysis for studies reporting adjusted and crude odds ratios (ORs) with 95% CIs. A subgroup analysis was related to the type of HS patient (general patients vs hospital patients) and age group (adults vs children and adults).
Five studies including 3950 HS patients were analyzed. We found that MS was pres-ent in 9.64% of HS patients (OR, 1.82; 95%, CI 1.39-2.25). Studies from tertiary care hospital dermatology clinics (OR, 2.82; 95% CI, 0.58-5.06) reported a greater risk for MS than studies carried out in patients treated outside hospitals (OR, 1.78; 95% CI, 1.34-2.22). Studies that included pediatric populations reported a significant association (OR, 2.10; 95% CI, 1.58-2.62).
Few of the included studies reported adjusted ORs.
HS patients have an increased risk for MS. Clinicians should consider screening HS patients for metabolic risk factors.</abstract><pmid>30846164</pmid><doi>10.1016/j.ad.2018.10.020</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1578-2190 |
| ispartof | Actas dermo-sifiliográficas (English ed.), 2019-05, Vol.110 (4), p.279-288 |
| issn | 1578-2190 |
| language | eng ; spa |
| recordid | cdi_proquest_miscellaneous_2189544410 |
| source | ScienceDirect Journals |
| subjects | Adult Age Factors Child Comorbidity Hidradenitis Suppurativa - epidemiology Hidradenitis Suppurativa - physiopathology Hospitalization Humans Metabolic Syndrome - epidemiology Metabolic Syndrome - physiopathology Observational Studies as Topic Odds Ratio Risk Tertiary Care Centers |
| title | Association Between Hidradenitis Suppurativa and Metabolic Syndrome: A Systematic Review and Meta-analysis |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T20%3A51%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20Between%20Hidradenitis%20Suppurativa%20and%20Metabolic%20Syndrome:%20A%20Systematic%20Review%20and%20Meta-analysis&rft.jtitle=Actas%20dermo-sifiliogr%C3%A1ficas%20(English%20ed.)&rft.au=Rodr%C3%ADguez-Zu%C3%B1iga,%20M%20J%20M&rft.date=2019-05&rft.volume=110&rft.issue=4&rft.spage=279&rft.epage=288&rft.pages=279-288&rft.eissn=1578-2190&rft_id=info:doi/10.1016/j.ad.2018.10.020&rft_dat=%3Cproquest_pubme%3E2189544410%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p126t-6d411969d49729d2fa7b35e3704be490867bc8a06ffac612de5f91dccf6c23503%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2189544410&rft_id=info:pmid/30846164&rfr_iscdi=true |