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H3K27M-Positive Primary Spinal Glioblastoma Presenting with Hemorrhage—A Rare Clinical Entity
Primary spinal glioblastoma multiforme is a rare and aggressive spinal tumor with dismal outcomes We have presented an unusual case—the first, to the best of our knowledge, to be reported—with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multif...
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| Published in: | World neurosurgery 2019-06, Vol.126, p.223-227 |
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| Main Authors: | , , , |
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| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c356t-64487819cf3fa6953408ab5c9df490ee7ace4a9cb44798bbbf9da8b3d57e1ef63 |
| container_end_page | 227 |
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| container_title | World neurosurgery |
| container_volume | 126 |
| creator | Uppar, Alok Konar, Subhas K. B.N., Nandeesh Shukla, Dhaval |
| description | Primary spinal glioblastoma multiforme is a rare and aggressive spinal tumor with dismal outcomes
We have presented an unusual case—the first, to the best of our knowledge, to be reported—with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay.
The tumor was positive for histone molecular alteration, H3K27M. |
| doi_str_mv | 10.1016/j.wneu.2019.03.025 |
| format | article |
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We have presented an unusual case—the first, to the best of our knowledge, to be reported—with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay.
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We have presented an unusual case—the first, to the best of our knowledge, to be reported—with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay.
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We have presented an unusual case—the first, to the best of our knowledge, to be reported—with intratumoral hemorrhage and sudden-onset quadriplegia in a patients with primary spinal glioblastoma multiforme. The patient underwent emergency surgical decompression. The patient died after a prolonged intensive care unit stay.
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| fulltext | fulltext |
| identifier | ISSN: 1878-8750 |
| ispartof | World neurosurgery, 2019-06, Vol.126, p.223-227 |
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| language | eng |
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| source | Elsevier |
| subjects | Adult Biomarkers, Tumor - metabolism Cervical Cord - metabolism Cervical Cord - pathology Cervical Cord - surgery Decompression, Surgical Fatal Outcome Female Glioblastoma - complications Glioblastoma - metabolism Glioblastoma - pathology Glioblastoma - surgery H3K27M Hemorrhage Hemorrhage - etiology Hemorrhage - metabolism Hemorrhage - pathology Hemorrhage - surgery Humans Primary spinal glioblastoma Spinal Cord Neoplasms - complications Spinal Cord Neoplasms - metabolism Spinal Cord Neoplasms - pathology Spinal Cord Neoplasms - surgery Surgery |
| title | H3K27M-Positive Primary Spinal Glioblastoma Presenting with Hemorrhage—A Rare Clinical Entity |
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