Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog

An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial de...

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Bibliographic Details
Published in:Veterinary radiology & ultrasound 2021-05, Vol.62 (3), p.E20-E25
Main Authors: Hughes, Jonathan R., Taylor‐Brown, Frances E., Greville‐Heygate, Oliver, Constantino‐Casas, Fernando, Williams, David L., Genain, Marie‐Aude
Format: Article
Language:English
Subjects:
brain neoplasia
calvarium
skull defect
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Summary:An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.
ISSN:1058-8183
1740-8261
DOI:10.1111/vru.12732