Occurrence and distribution of antibiotics and antibiotic resistant genes in water and sediments of urban rivers with black-odor water in Guangzhou, South China

• Published in: The Science of the total environment 2019-06, Vol.670, p.170-180
• Main Authors: Huang, Yu-Hong, Liu, Yue, Du, Pei-Pei, Zeng, Li-Juan, Mo, Ce-Hui, Li, Yan-Wen, Lü, Huixiong, Cai, Quan-Ying
• Format: Article
• Language: English
• Subjects: Antibiotic resistant genes; Antibiotics; Black-odor water; Heavy metals; Sediment; Urban rivers
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2019.03.168

Urban rivers in some countries have been heavily polluted and the water became black and odor. Nevertheless, only few studies reported the occurrence of antibiotics and their corresponding antibiotic resistant genes (ARGs) in urban rivers with black-odor water with and without remediation. In this study, nine antibiotics (belonging to sulfonamides, tetracyclines, quinolones, and macrolides) and their corresponding ARGs in water and sediments of six urban rivers in Guangzhou, South China were analyzed to investigate their spatial distribution and the influence of water remediation. The concentrations of individual antibiotics varied from ND (not detectable) to 2702 ng/L and ND to 449 μg/kg in surface water and sediments, respectively. Norfloxacin displayed the highest average concentrations, followed by ciprofloxacin. The relative abundance of quinolone-resistance gene qnrA (~103 ARGs/16S rRNA) was the highest, followed by tetracyclines-resistance genes tetC (~10−2 ARGs/16S rRNA). The antibiotics and ARGs in sediments from various rivers exhibited distinct spatial distribution with large variation from upstream to downstream. Generally, levels of antibiotics and tetracyclines-resistance genes (tetA, tetC and tetM) in urban rivers with black-odor water (affected by industrial and domestic sewage) were higher than those in remediated urban rivers. Significant positive correlations were observed only between the relative abundances of tetA (or tetC) with the concentrations of some antibiotics (e.g., ciprofloxacin and norfloxacin). TetA was also significantly positively correlated with the concentrations of Ni, Cr, and As in sediments. This study found that urban rivers remediated with dredging might lower antibiotic levels in sediment, but high relative abundance of certain ARGs (e.g., tetB, qnrA) may still exist. [Display omitted] •This study firstly reports the antibiotics and ARGs in urban rivers with black-odor water.•The antibiotics and ARGs in sediments exhibited distinct spatial distribution.•Black-odor river displayed high antibiotics and ARG levels in water and sediments.•Remediated urban rivers showed low level of antibiotics but high level of certain ARGs.