Structure of Rat Testicles after Intravenous Injection of Nanosized Magnetite Particles

The structure of the testicles was studied in adult rats in 120 days after a single intravenous injection of chitosan-modified (magnetic nanospheres) and lipid-modified (magnetoliposomes) nanosized magnetite particles. Perls histochemical reaction detected in the testicular interstitial connective t...

Full description

Saved in:
Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2019-03, Vol.166 (5), p.680-685
Main Authors: Mil’to, I. V., Sukhodolo, I. V., Ivanova, V. V., Usov, V. Yu
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Cell Biology
Chitosan
Injection
Internal Medicine
Intravenous administration
Laboratory Medicine
Magnetite
Morphology and Pathomorphology
Murals
Nanoparticles
Pathology
Rodents
Spermatogenesis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The structure of the testicles was studied in adult rats in 120 days after a single intravenous injection of chitosan-modified (magnetic nanospheres) and lipid-modified (magnetoliposomes) nanosized magnetite particles. Perls histochemical reaction detected in the testicular interstitial connective tissue the cells which absorbed and accumulated magnetite nanoparticles. The dynamics of spermatogenesis index and the count of Perls + cells in the rat testicles were traced throughout the experiment. The studied modified nanosized magnetite particles did not penetrate through the blood—testicle barrier in rats.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-019-04417-z