Foetal radiation exposure caused by mechanical thrombectomy in large-vessel ischaemic stroke in pregnancy

Purpose There is overwhelming evidence for the clinical benefits that are derived following mechanical thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergo...

Full description

Saved in:
Bibliographic Details
Published in:Neuroradiology 2019-04, Vol.61 (4), p.443-449
Main Authors: Tse, George H., Balian, Vartan, Charalampatou, Paraskevi, Maliakal, Paul, Nayak, Sanjeev, Dyde, Richard, Nagaraja, Sanjoy
Format: Article
Language:English
Subjects:
Adult
Brain Ischemia - diagnostic imaging
Brain Ischemia - surgery
Computed tomography
Computed Tomography Angiography - methods
Diagnostic systems
England
Exposure
Feasibility studies
Female
Fetus - radiation effects
Fetuses
Health risks
Humans
Imaging
Interventional Neuroradiology
Medical imaging
Medicine
Medicine & Public Health
Nervous system
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Patients
Pregnancy
Pregnancy Complications, Cardiovascular - diagnostic imaging
Pregnancy Complications, Cardiovascular - surgery
Radiation
Radiation Dosage
Radiation effects
Radiology
Stroke
Stroke - diagnostic imaging
Stroke - surgery
Thrombectomy - methods
Trauma
Whole Body Imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose There is overwhelming evidence for the clinical benefits that are derived following mechanical thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone mechanical thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy. Methods We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations. Results Three cases of mechanical thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and mechanical thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA ( p  
ISSN:0028-3940
1432-1920
DOI:10.1007/s00234-019-02163-7