Treatment of patients with brain metastases from a melanoma

Whereas immune checkpoint inhibitors of serine/threonine protein kinase B-raf therapy dramatically changed metastatic outcomes of patients with melanoma, they remain at high risk of brain extension. Additional local treatment can be offered in this situation such as surgery and or stereotactic radio...

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Bibliographic Details
Published in:Cancer radiothérapie 2019-04, Vol.23 (2), p.147-150
Main Authors: Modesto, A, Chira, C, Sol, J-C, Lubrano, V, Boulinguez, S, Pagès, C, Sibaud, V, Gomez-Roca, C, Moyal, É, Meyer, N
Format: Article
Language:fre
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Summary:Whereas immune checkpoint inhibitors of serine/threonine protein kinase B-raf therapy dramatically changed metastatic outcomes of patients with melanoma, they remain at high risk of brain extension. Additional local treatment can be offered in this situation such as surgery and or stereotactic radiotherapy. In this review article, we describe the different options with published data and their optimal timing.
ISSN:1769-6658
DOI:10.1016/j.canrad.2018.05.006