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Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia

Two new bisindole alkaloids, leucophyllinines A ( 1 ) and B ( 2 ) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia , and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial a...

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Bibliographic Details
Published in:Journal of natural medicines 2019-06, Vol.73 (3), p.533-540
Main Authors: Tang, Yiming, Nugroho, Alfarius Eko, Hirasawa, Yusuke, Tougan, Takahiro, Horii, Toshihiro, Hadi, A. Hamid A., Morita, Hiroshi
Format: Article
Language:English
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Summary:Two new bisindole alkaloids, leucophyllinines A ( 1 ) and B ( 2 ) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia , and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
ISSN:1340-3443
1861-0293
DOI:10.1007/s11418-019-01297-5