Vein Graft Patency Rates With Aspirin Plus Clopidogrel Following Coronary Artery Bypass Grafting

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, “In patients who have undergone Coronary Artery Bypass Grafting, does aspirin plus clopidogrel postoperatively improve vein graft patency when compared to aspirin alone?” Altogether,...

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Bibliographic Details
Published in:Heart, lung & circulation lung & circulation, 2020-01, Vol.29 (1), p.162-163
Main Authors: De Bono, Joshua A., Conte, Sean M., Florisson, Daniel S., Davies, Reece A., Newcomb, Andrew E.
Format: Article
Language:English
Subjects:
Aspirin
Clopidogrel
Coronary artery bypass grafting
Graft patency
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Summary:A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, “In patients who have undergone Coronary Artery Bypass Grafting, does aspirin plus clopidogrel postoperatively improve vein graft patency when compared to aspirin alone?” Altogether, 165 papers were found using the reported search, of which five represented the best evidence to answer the clinical question. Overall analysis of these papers demonstrated similar rates of vein graft patency between the two groups. There was no difference between the groups with regard to mortality, adverse bleeding-related outcomes, or composite vascular events.
ISSN:1443-9506
1444-2892
DOI:10.1016/j.hlc.2019.02.191