Preventing treatment abandonment for children with solid tumors: A single‐center experience in Brazil

Background High rates of treatment abandonment have been considered one of the major limitations to achieving high cure rates of childhood cancer in developing countries. The aims of this study were to report the prevalence and factors associated with treatment abandonment for children diagnosed wit...

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Bibliographic Details
Published in:Pediatric blood & cancer 2019-07, Vol.66 (7), p.e27724-n/a
Main Authors: Ferman, Sima, Lima, Fernanda Ferreira da Silva, Lage, Carollyne Rodrigues Souza, da Hora, Senir Santos, Vianna, Danielle Tavares, Thuler, Luiz Claudio
Format: Article
Language:English
Subjects:
abandonment
Adolescent
Adult
Brazil - epidemiology
Child
Child, Preschool
childhood cancer
Children
Developing countries
Female
Hematology
Humans
Infant
Infant, Newborn
LDCs
low‐ and middle‐income country
Male
Oncology
Patients
Pediatrics
Prevalence
refusal
Retina
Retinal Neoplasms - diagnosis
Retinal Neoplasms - epidemiology
Retinal Neoplasms - therapy
Retinoblastoma
Retinoblastoma - diagnosis
Retinoblastoma - epidemiology
Retinoblastoma - therapy
Retrospective Studies
Socioeconomic Factors
Solid tumors
Statistical analysis
Treatment Refusal
Tumors
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Summary:Background High rates of treatment abandonment have been considered one of the major limitations to achieving high cure rates of childhood cancer in developing countries. The aims of this study were to report the prevalence and factors associated with treatment abandonment for children diagnosed with solid tumors in one reference center in Brazil and to describe effective strategies to prevent it. Procedures A retrospective review was conducted using data from 1139 children (0–18 years) treated for solid tumors at the Brazilian National Cancer Institute, during the period between January 2012 and December 2017. Treatment abandonment was defined as recommended by the International Society of Pediatric Oncology. The impact of implementing a patient‐tracking system was evaluated. Descriptive statistics were used to analyze patient characteristics. Chi‐square test was used for statistical analysis, with the significance level
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.27724