Surgical Outcomes for the Treatment of Velopharyngeal Insufficiency in 22q11.2 Deletion Syndrome

This study aimed to compare outcomes of concomitant palatoplasty and sphincter pharyngoplasty with pharyngeal flap and sphincter pharyngoplasty alone for the treatment of velopharyngeal insufficiency in patients with 22q11.2 deletion syndrome. Thirty-one cases were identified for inclusion in the st...

Full description

Saved in:
Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2019-08, Vol.161 (2), p.348-351
Main Authors: Bohm, Lauren A., Miller, Jessa E., Morrell, Noëlle, Sidman, James D., Roby, Brianne B.
Format: Article
Language:English
Subjects:
22q11.2 deletion syndrome
Adolescent
Child
Child, Preschool
DiGeorge syndrome
DiGeorge Syndrome - complications
Female
Furlow palatoplasty
Humans
hypernasality
Male
Palate, Soft - surgery
Pharynx - surgery
Retrospective Studies
speech outcomes
sphincter pharyngoplasty
Treatment Outcome
velocardiofacial syndrome
velopharyngeal insufficiency
Velopharyngeal Insufficiency - etiology
Velopharyngeal Insufficiency - surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study aimed to compare outcomes of concomitant palatoplasty and sphincter pharyngoplasty with pharyngeal flap and sphincter pharyngoplasty alone for the treatment of velopharyngeal insufficiency in patients with 22q11.2 deletion syndrome. Thirty-one cases were identified for inclusion in the study. Patients were separated into 3 surgical groups: combined palatoplasty and sphincter pharyngoplasty (n = 11), pharyngeal flap (n = 7), and sphincter pharyngoplasty (n = 13). Outcome measures included perceptual speech analyses, surgical complications, and revision rates. There were no differences in preoperative speech analysis scores (P = .31). The combined palatoplasty and sphincter pharyngoplasty procedure had similar speech outcomes compared to pharyngeal flap, and both were significantly better than sphincter pharyngoplasty alone. Complication rates (P = .61) and the need for revision surgery (P = .25) were similar among all 3 groups. Concomitant palatoplasty and sphincter pharyngoplasty may be an alternative treatment for velopharyngeal insufficiency in children with 22q11.2 deletion syndrome.
ISSN:0194-5998
1097-6817
DOI:10.1177/0194599819839958