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BK virus: Current understanding of pathogenicity and clinical disease in transplantation

Summary BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review cover...

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Bibliographic Details
Published in:Reviews in medical virology 2019-07, Vol.29 (4), p.e2044-n/a
Main Authors: Chong, Stephanie, Antoni, Michelle, Macdonald, Andrew, Reeves, Matthew, Harber, Mark, Magee, Ciara N.
Format: Article
Language:English
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Summary:Summary BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.
ISSN:1052-9276
1099-1654
DOI:10.1002/rmv.2044