Early predictors of functional disability in Guillain–Barré Syndrome

This study investigated the predictors of prognosis at admission and after the first month in Guillain–Barré syndrome (GBS) patients. This retrospective study used the electronic records of 81 GBS patients. Age, gender, previous GBS history, antecedent febrile illness and presence of cranial nerve d...

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Bibliographic Details
Published in:Acta neurologica Belgica 2019-12, Vol.119 (4), p.555-559
Main Author: Tunç, Abdulkadir
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Biomedical and Life Sciences
Biomedicine
Female
Guillain-Barre Syndrome - blood
Guillain-Barre Syndrome - diagnosis
Humans
Lymphocytes
Male
Medicine/Public Health
Middle Aged
Neurology
Neuroradiology
Neurosciences
Neutrophils
Original Article
Prognosis
Retrospective Studies
Serum Albumin
Sodium - blood
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Summary:This study investigated the predictors of prognosis at admission and after the first month in Guillain–Barré syndrome (GBS) patients. This retrospective study used the electronic records of 81 GBS patients. Age, gender, previous GBS history, antecedent febrile illness and presence of cranial nerve dysfunction were recorded. Detailed neurological examinations, routine biochemical and haematological investigations, cerebrospinal fluid (CSF) analysis and electrophysiological studies, GBS subtypes and treatments were assessed. Hughes disability scores (HDSs) were evaluated at the end of the first day and first month. The GBS patient group included 44 male (54.3%) and 37 female (45.7%) patients. The mean age was 52.2 ± 18.5. The mean HDS score was 2.96 at admission and 1.94 at the end of the first month. Plasma sodium, albumin, and CSF protein levels were significantly correlated with low admission HDS scores ( p  = 0.03, p  = 0.011, p  = 0.036, and p  
ISSN:0300-9009
2240-2993
DOI:10.1007/s13760-019-01133-3