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Medical Algorithms: Diagnosis and treatment of Hymenoptera venom allergy

Diagnosis of Hymenoptera venom allergy (HVA) is straightforward in the majority of patients, but can be challenging in double positive and test negative patients. Test results sometimes can be confusing as patients with high skin test reactivity and high specific IgE (sIgE) levels are not at risk fo...

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Bibliographic Details
Published in:Allergy (Copenhagen) 2019-10, Vol.74 (10), p.2016-2018
Main Authors: Sturm, Gunter J., Arzt‐Gradwohl, Lisa, Varga, Eva‐ M.
Format: Article
Language:English
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Summary:Diagnosis of Hymenoptera venom allergy (HVA) is straightforward in the majority of patients, but can be challenging in double positive and test negative patients. Test results sometimes can be confusing as patients with high skin test reactivity and high specific IgE (sIgE) levels are not at risk for severe systemic sting reactions (SSR), and conversely, patients with weakly positive or even negative tests can experience severe SSR. Venom immunotherapy (VIT) is safe, highly effective, and recommended in patients with moderate to severe SSR and in patients with SSR confined to generalized skin symptoms if quality of life is impaired.
ISSN:0105-4538
1398-9995
DOI:10.1111/all.13817