Highly Oxidized Graphene Quantum Dots from Coal as Efficient Antioxidants

Graphene quantum dots (GQDs) have recently been employed in various fields including medicine as antioxidants, primarily because of favorable biocompatibility in comparison to common inorganic quantum dots, although the structural features that lead to the biological activities of GQDs are poorly un...

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Bibliographic Details
Published in:ACS applied materials & interfaces 2019-05, Vol.11 (18), p.16815-16821
Main Authors: Nilewski, Lizanne, Mendoza, Kimberly, Jalilov, Almaz S, Berka, Vladimir, Wu, Gang, Sikkema, William K. A, Metzger, Andrew, Ye, Ruquan, Zhang, Rui, Luong, Duy Xuan, Wang, Tuo, McHugh, Emily, Derry, Paul J, Samuel, Errol Loïc, Kent, Thomas A, Tsai, Ah-Lim, Tour, James M
Format: Article
Language:English
Subjects:
Antioxidants - chemistry
Antioxidants - pharmacology
Biocompatible Materials - chemistry
Biocompatible Materials - pharmacology
Coal
Graphite - chemistry
Graphite - pharmacology
Humans
Oxidation-Reduction
Polyethylene Glycols - chemistry
Quantum Dots - chemistry
Superoxide Dismutase - chemistry
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Summary:Graphene quantum dots (GQDs) have recently been employed in various fields including medicine as antioxidants, primarily because of favorable biocompatibility in comparison to common inorganic quantum dots, although the structural features that lead to the biological activities of GQDs are poorly understood. Here, we report that coal-derived GQDs and their poly­(ethylene glycol)-functionalized derivatives serve as efficient antioxidants, and we evaluate their electrochemical, chemical, and in vitro biological activities.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.9b01082