Systematic Analysis of the Impact of Diagnostic Delay on Bowel Damage in Paediatric Versus Adult Onset Crohn's Disease

Length of diagnostic delay is associated with bowel strictures and intestinal surgery in adult patients with Crohn's disease [CD]. Here we assessed whether diagnostic delay similarly impacts on the natural history of paediatric CD patients. Data from the Swiss IBD Cohort Study were analysed. Fr...

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Bibliographic Details
Published in:Journal of Crohn's and colitis 2019-09, Vol.13 (10), p.1334-1342
Main Authors: Schoepfer, Alain, Santos, Jessica, Fournier, Nicolas, Schibli, Susanne, Spalinger, Johannes, Vavricka, Stephan, Safroneeva, Ekaterina, Aslan, Nurullah, Rogler, Gerhard, Braegger, Christian, Nydegger, Andreas
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age of Onset
Child
Crohn Disease - complications
Crohn Disease - diagnosis
Crohn Disease - pathology
Delayed Diagnosis - adverse effects
Female
Humans
Intestines - pathology
Male
Switzerland
Time Factors
Young Adult
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Summary:Length of diagnostic delay is associated with bowel strictures and intestinal surgery in adult patients with Crohn's disease [CD]. Here we assessed whether diagnostic delay similarly impacts on the natural history of paediatric CD patients. Data from the Swiss IBD Cohort Study were analysed. Frequency of CD-related complications [bowel stenosis, perianal fistula, internal fistula, any fistula, resection surgery, fistula/abscess surgery, any complication] at diagnosis and in the long term [up to 30 years after CD diagnosis] was compared between paediatric patients [diagnosed
ISSN:1873-9946
1876-4479
DOI:10.1093/ecco-jcc/jjz065