Quality of life among patients after cystoprostatectomy as the treatment for locally advanced prostate cancer with bladder invasion

This study aimed to evaluate the changes of patients' quality of life (QoL) after cystoprostatectomy as a treatment for locally advanced prostate cancer (LAPC) with the bladder invasion and to determine risk factors for postoperative poor QoL. Between Jan 2012 and December 2015, 27 patients who...

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Bibliographic Details
Published in:The aging male 2020-12, Vol.23 (5), p.847-853
Main Authors: Yuan, Peng, Wang, Shen, Sun, Xifeng, Xu, Hua, Ye, Zhangqun, Chen, Zhiqiang
Format: Article
Language:English
Subjects:
Aging
Bladder
bladder invasion
Cystoprostatectomy
FACT-P questionnaire
Humans
locally advanced prostate cancer
Male
Mens health
Prostate cancer
Prostatic Neoplasms - surgery
Quality of Life
Questionnaires
Retrospective Studies
Urinary Bladder Neoplasms - surgery
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Summary:This study aimed to evaluate the changes of patients' quality of life (QoL) after cystoprostatectomy as a treatment for locally advanced prostate cancer (LAPC) with the bladder invasion and to determine risk factors for postoperative poor QoL. Between Jan 2012 and December 2015, 27 patients who received cystoprostatectomy for LAPC with the bladder invasion were retrospectively included. QoL was assessed with the functional assessment of cancer therapy-prostate (FACT-P) questionnaire scores. Determinants for postoperative poor QoL were investigated using univariate and multivariate regression analysis. Three-year overall survival, biochemical progression-free survival, and clinical progress-free survival were 88.89%, 62.96% and 77.78%, respectively. Preoperative symptoms of hematuria, urinary frequency, and dysuria were well alleviated after cystoprostatectomy. Moreover, FACT-P questionnaire scores at 6 months and 1 year after cystoprostatectomy were significantly higher than preoperative scores. Univariate and multivariable analysis (p 
ISSN:1368-5538
1473-0790
DOI:10.1080/13685538.2019.1604653