Multinodular and vacuolating neuronal tumour of the cerebrum: a rare neuroimaging incidentaloma or a potentially treatable cause of focal epilepsy?

ABSTRACT Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult‐onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplas...

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Bibliographic Details
Published in:Epileptic disorders 2019-04, Vol.21 (2), p.209-214
Main Authors: Baščarević, Vladimir, Pejović, Aleksa T., Ristić, Aleksandar J., Vojvodić, Nikola, Raičević, Savo, Đukić, Tijana, Brajković, Leposava, Sokić, Dragoslav
Format: Article
Language:English
Subjects:
Brain Neoplasms - complications
Brain Neoplasms - diagnosis
Brain Neoplasms - pathology
Brain Neoplasms - surgery
Case reports
Cerebrum
DNET
Electroencephalography
Epilepsy
Epilepsy, Temporal Lobe - diagnosis
Epilepsy, Temporal Lobe - etiology
Epilepsy, Temporal Lobe - surgery
Female
Humans
Magnetic Resonance Imaging
Middle Aged
multinodular vacuolating neuronal tumour
Neuroimaging
seizure
Seizures
surgery
Temporal lobe
Tumors
WHO tumour classification
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Summary:ABSTRACT Multinodular and vacuolating neuronal tumour (MVNT) of the cerebrum is a relatively new, well defined histopathological and neuroradiological entity, in many cases associated with an early adult‐onset epilepsy. These lesions have an indolent course and resemble both malformative and neoplastic processes, combining a focal developmental anomaly and a low‐grade tumour. Herein, we report a case of a 48‐year‐old female patient with left temporal lobe epilepsy associated with MVNT. In addition, a comprehensive review of all the previously published cases is provided with a focus on seizure‐related cases, surgical treatment, and postoperative outcome.
ISSN:1294-9361
1950-6945
DOI:10.1684/epd.2019.1045