Waitlist Mortality of Patients With Amyloid Cardiomyopathy who Are Listed for Heart Transplantation and Implications for Organ Allocation

Outcomes of patients with amyloid cardiomyopathy (ACM) undergoing heart transplantation have been reported, but there are scant data concerning the waitlist mortality (WLM) of these patients. The aim of this study was to investigate whether patients with ACM have higher waitlist mortality compared t...

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Bibliographic Details
Published in:Journal of cardiac failure 2019-09, Vol.25 (9), p.767-771
Main Authors: Panhwar, Muhammad S., AL-KINDI, SADEER G., TOFOVIC, DAVID, OLIVEIRA, GUILHERME H., GINWALLA, MAHAZARIN
Format: Article
Language:English
Subjects:
Amyloid
heart transplantation
organ allocation
waitlist
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Summary:Outcomes of patients with amyloid cardiomyopathy (ACM) undergoing heart transplantation have been reported, but there are scant data concerning the waitlist mortality (WLM) of these patients. The aim of this study was to investigate whether patients with ACM have higher waitlist mortality compared to those with other types of cardiomyopathies. We queried the United Network for Organ Sharing registry for all patients (age ≥ 18 years) listed for heart transplantation between 2008 and 2015. We compared patients with ACM to those with dilated cardiomyopathy (DCM) or idiopathic restrictive cardiomyopathy (RCM) for WLM and waitlist mortality or delisting for deterioration (WLM/D). We identified 306 patients with ACM, 183 with RCM and 8416 with DCM. Patients with ACM were older (ACM 61 vs RCM 49 vs DCM 51 years, P  <  .001), were more likely to be male (82% vs 60% vs 73%, P  <  .001) but less likely to be listed as status 1A (16% vs 18% vs 23%, P
ISSN:1071-9164
1532-8414
DOI:10.1016/j.cardfail.2019.04.011