Management of tuberculosis of the central nervous system: Our experience

[...]it was difficult to be sure of the diagnosis preoperative ly. Between 2012 and 2016, among the 18 827 CNS 'tumours' submitted to biopsy there were only 95 tubercular lesions-50 intracranial and 45 spinal. [...]barring a few exceptions, the standard treatment for ICtm now is medical th...

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Bibliographic Details
Published in:The National medical journal of India 2018-05, Vol.31 (3), p.151-155
Main Author: Tandon, P N
Format: Article
Language:English
Subjects:
BCG
Central nervous system
Developing countries
Hymns
Infections
LDCs
Meningitis
Nervous system
Neurology
Neurosciences
Neurosurgery
Prehistory
Surgeons
Tuberculosis
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Summary:[...]it was difficult to be sure of the diagnosis preoperative ly. Between 2012 and 2016, among the 18 827 CNS 'tumours' submitted to biopsy there were only 95 tubercular lesions-50 intracranial and 45 spinal. [...]barring a few exceptions, the standard treatment for ICtm now is medical therapy and not surgery. [...]tuberculosis had not read the books' and 'the books failed to keep up' with its 'devious ways of evading its eradication'. [...]we ended up re-exploring practically all aspects of neuro tuberculosis- its pathology, pathogenesis, clinical manifestations, diagnosis and management of diverse syndromes had to be redefined and elaborated and new strategies for treatment evaluated. While no revolutionary discoveries were made, we had the satisfaction of adding some valuable new information and improving the management of our patients. [...]we were able to develop an experimental model of the disease in Rhesus monkeys, and were pioneers in studying its diverse effects on CSF pathways and flow dynamics, and were among the first to describe its image morphology on CT.
ISSN:0970-258X
DOI:10.4103/0970-258X.255758