RiboD: a comprehensive database for prokaryotic riboswitches

Abstract Summary Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using...

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Bibliographic Details
Published in:Bioinformatics 2019-09, Vol.35 (18), p.3541-3543
Main Authors: Mukherjee, Sumit, Das Mandal, Sukhen, Gupta, Nikita, Drory-Retwitzer, Matan, Barash, Danny, Sengupta, Supratim
Format: Article
Language:English
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Summary:Abstract Summary Riboswitches are cis-regulatory non-coding genomic segments that control the expression of downstream genes by undergoing conformational change upon ligand binding. We present a comprehensive database of prokaryotic riboswitches that allows the user to search for riboswitches using multiple criteria, extract information about riboswitch location and gene/operon it regulates. RiboD provides a very useful resource that can be utilized for the better understanding of riboswitch-based gene regulation in bacteria and archaea. Availability and implementation RiboD can be freely accessed on the web at http://ribod.iiserkol.ac.in/.
ISSN:1367-4803
1460-2059
1367-4811
DOI:10.1093/bioinformatics/btz093