Feasibility of low-dose CT with spectral shaping and third-generation iterative reconstruction in evaluating interstitial lung diseases associated with connective tissue disease: an intra-individual comparison study

Objectives To investigate the feasibility of low-dose CT (LDCT) with tin filtration and third-generation iterative reconstruction (IR) in evaluating interstitial lung diseases associated with connective tissue disease (CTD-ILD). Methods Fifty-three consecutive adult patients with CTD-ILD underwent r...

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Bibliographic Details
Published in:European radiology 2019-09, Vol.29 (9), p.4529-4537
Main Authors: Xu, Xiaoli, Sui, Xin, Song, Lan, Huang, Yao, Ge, Yingqian, Jin, Zhengyu, Song, Wei
Format: Article
Language:English
Subjects:
Adult
Aged
Algorithms
Bronchi
Bronchus
Chest
Connective tissue diseases
Connective Tissue Diseases - complications
Connective Tissue Diseases - diagnostic imaging
Connective tissues
Diagnostic Radiology
Feasibility Studies
Female
Filtration
Health risk assessment
Humans
Image acquisition
Image quality
Image reconstruction
Imaging
Internal Medicine
Interventional Radiology
Iterative methods
Lesions
Lung diseases
Lung Diseases, Interstitial - diagnostic imaging
Lung Diseases, Interstitial - etiology
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Noise
Optimization
Radiation
Radiation Dosage
Radiographic Image Interpretation, Computer-Assisted - methods
Radiology
Tin
Tissues
Tomography, X-Ray Computed - methods
Ultrasound
Visualization
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Summary:Objectives To investigate the feasibility of low-dose CT (LDCT) with tin filtration and third-generation iterative reconstruction (IR) in evaluating interstitial lung diseases associated with connective tissue disease (CTD-ILD). Methods Fifty-three consecutive adult patients with CTD-ILD underwent regular-dose chest CT (RDCT) at 110 kVp followed by LDCT with tin-filtered 100 kVp. RDCT was reconstructed with filtered back projection (FBP) and advanced modeled iterative reconstruction (ADMIRE); LDCT was reconstructed with ADMIRE. Image noise, streak artifact, image quality, and visualization of normal and abnormal CT features were evaluated and compared among RDCT-ADMIRE, RDCT-FBP, and LDCT-ADMIRE groups. Results The mean radiation dose of LDCT was reduced to 20% of RDCT. Objective image noise of RDCT-ADMIRE (38.08 ± 6.37 HU), LDCT-ADMIRE (51.68 ± 9.06 HU), and RDCT-FBP (62.09 ± 10.95 HU) increased progressively ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-018-5969-y