Intra-individual comparison of conventional and simultaneous multislice-accelerated diffusion-weighted imaging in upper abdominal solid organs: value of ADC normalization using the spleen as a reference organ

Purpose To compare the apparent diffusion coefficient (ADC) value of conventional diffusion-weighted imaging (cDWI) to simultaneous multislice-accelerated DWI (sDWI) and to evaluate the possibility of ADC normalization using the spleen as a reference organ. Methods We retrospectively evaluated 92 pa...

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Bibliographic Details
Published in:Abdominal imaging 2019-05, Vol.44 (5), p.1808-1815
Main Authors: Jang, Weon, Song, Ji Soo, Kwak, Hyo Sung, Hwang, Seung Bae, Paek, Mun Young
Format: Article
Language:English
Subjects:
Abdomen
Correlation coefficient
Correlation coefficients
Diffusion
Diffusion coefficient
Gastroenterology
Hepatobiliary
Hepatology
Imaging
Kidneys
Liver
Magnetic resonance imaging
Medical imaging
Medicine
Medicine & Public Health
NMR
Nuclear magnetic resonance
Organs
Pancreas
Radiology
Spleen
Statistical analysis
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Summary:Purpose To compare the apparent diffusion coefficient (ADC) value of conventional diffusion-weighted imaging (cDWI) to simultaneous multislice-accelerated DWI (sDWI) and to evaluate the possibility of ADC normalization using the spleen as a reference organ. Methods We retrospectively evaluated 92 patients (68 men, 24 women; mean age 60.0 years) who underwent liver magnetic resonance imaging (MRI) including both cDWI and sDWI. sDWI was obtained with an acceleration factor of 2. ADC values were measured from the right liver lobe, left liver lobe, spleen, pancreas, right kidney, and left kidney. ADC values of the spleen were used for normalization. Paired sample t test, Pearson’s correlation coefficient, and Bland–Altman method were used for statistical analysis. Results ADC values of cDWI were significantly lower than sDWI in all six anatomic regions ( p 
ISSN:2366-004X
2366-0058
DOI:10.1007/s00261-019-01924-5